Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AXIN1 All Species: 26.97
Human Site: T275 Identified Species: 53.94
UniProt: O15169 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15169 NP_003493.1 862 95635 T275 P Q K L L L E T A A P R V S S
Chimpanzee Pan troglodytes XP_001152990 821 90810 T275 P Q K L L L E T A A P R V S C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852321 867 95820 T275 T Q K L L L E T A A P R A S S
Cat Felis silvestris
Mouse Mus musculus O35625 863 96295 T275 T Q K L L L E T A A P R A P S
Rat Rattus norvegicus O70239 827 92266 T275 T Q K L L L E T A A P R A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508740 844 93228 T257 V V G L S S K T L R A T A N V
Chicken Gallus gallus O42400 841 94913 T275 T Q K L L L E T A T Q R A T S
Frog Xenopus laevis Q9YGY0 842 94441 S275 S Q K L A L D S S S H C A G S
Zebra Danio Brachydanio rerio P57094 835 94310 T278 T Q K L P L E T V P Q R V A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V407 745 81700 S248 P A G T C S A S G S V Y G P S
Honey Bee Apis mellifera XP_001120373 693 78297 Q209 L Q Y V Q S C Q N P D S G G C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781992 855 95982 D259 Q A G S L T A D L L F R S S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 N.A. 86.6 N.A. 87 84.2 N.A. 43.2 73 67.5 64 N.A. 21.8 27.2 N.A. 33
Protein Similarity: 100 95.1 N.A. 91.2 N.A. 91.1 88.1 N.A. 59.4 82.9 79.4 74.8 N.A. 38 42.4 N.A. 50.3
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 80 80 N.A. 13.3 66.6 33.3 53.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 93.3 N.A. 86.6 N.A. 80 80 N.A. 26.6 73.3 60 66.6 N.A. 26.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 9 0 17 0 50 42 9 0 50 9 0 % A
% Cys: 0 0 0 0 9 0 9 0 0 0 0 9 0 0 17 % C
% Asp: 0 0 0 0 0 0 9 9 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 25 0 0 0 0 0 9 0 0 0 17 17 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 67 0 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 75 59 67 0 0 17 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 9 % N
% Pro: 25 0 0 0 9 0 0 0 0 17 42 0 0 25 0 % P
% Gln: 9 75 0 0 9 0 0 9 0 0 17 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 67 0 0 0 % R
% Ser: 9 0 0 9 9 25 0 17 9 17 0 9 9 34 59 % S
% Thr: 42 0 0 9 0 9 0 67 0 9 0 9 0 9 0 % T
% Val: 9 9 0 9 0 0 0 0 9 0 9 0 25 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _