KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN1
All Species:
25.15
Human Site:
Y286
Identified Species:
50.3
UniProt:
O15169
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15169
NP_003493.1
862
95635
Y286
R
V
S
S
S
R
R
Y
S
E
G
R
E
F
R
Chimpanzee
Pan troglodytes
XP_001152990
821
90810
Y286
R
V
S
C
S
R
R
Y
S
E
G
R
E
F
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852321
867
95820
Y286
R
A
S
S
S
R
R
Y
S
E
G
R
E
F
R
Cat
Felis silvestris
Mouse
Mus musculus
O35625
863
96295
Y286
R
A
P
S
S
R
R
Y
N
E
G
R
E
L
R
Rat
Rattus norvegicus
O70239
827
92266
Y286
R
A
P
S
S
R
R
Y
N
E
G
R
E
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
E268
T
A
N
V
R
A
T
E
T
V
E
N
G
Y
R
Chicken
Gallus gallus
O42400
841
94913
Y286
R
A
T
S
T
R
R
Y
S
E
G
R
E
F
R
Frog
Xenopus laevis
Q9YGY0
842
94441
L286
C
A
G
S
N
R
R
L
S
D
G
R
E
F
R
Zebra Danio
Brachydanio rerio
P57094
835
94310
Y289
R
V
A
N
S
K
R
Y
Q
D
N
R
E
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
S259
Y
G
P
S
T
S
A
S
S
S
G
S
I
S
A
Honey Bee
Apis mellifera
XP_001120373
693
78297
G220
S
G
G
C
P
S
S
G
S
S
R
E
M
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
N270
R
S
S
H
H
R
H
N
A
E
R
Y
Q
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
N.A.
86.6
N.A.
87
84.2
N.A.
43.2
73
67.5
64
N.A.
21.8
27.2
N.A.
33
Protein Similarity:
100
95.1
N.A.
91.2
N.A.
91.1
88.1
N.A.
59.4
82.9
79.4
74.8
N.A.
38
42.4
N.A.
50.3
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
73.3
73.3
N.A.
6.6
80
60
53.3
N.A.
20
6.6
N.A.
33.3
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
80
80
N.A.
26.6
93.3
73.3
86.6
N.A.
26.6
6.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
9
0
0
9
9
0
9
0
0
0
0
0
9
% A
% Cys:
9
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
59
9
9
67
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% F
% Gly:
0
17
17
0
0
0
0
9
0
0
67
0
9
0
0
% G
% His:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
9
9
9
0
0
9
17
0
9
9
0
0
0
% N
% Pro:
0
0
25
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Q
% Arg:
67
0
0
0
9
67
67
0
0
0
17
67
0
0
84
% R
% Ser:
9
9
34
59
50
17
9
9
59
17
0
9
0
17
0
% S
% Thr:
9
0
9
0
17
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
25
0
9
0
0
0
0
0
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
59
0
0
0
9
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _