KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN1
All Species:
15.15
Human Site:
Y578
Identified Species:
30.3
UniProt:
O15169
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15169
NP_003493.1
862
95635
Y578
H
G
A
R
S
R
G
Y
S
E
S
V
G
A
A
Chimpanzee
Pan troglodytes
XP_001152990
821
90810
Y578
H
G
A
R
S
R
G
Y
S
E
S
V
G
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852321
867
95820
H578
H
T
A
K
P
R
S
H
S
E
S
V
G
A
A
Cat
Felis silvestris
Mouse
Mus musculus
O35625
863
96295
S574
H
G
H
A
K
P
R
S
Y
S
E
N
A
G
T
Rat
Rattus norvegicus
O70239
827
92266
S574
H
G
H
A
K
P
R
S
Y
S
E
S
T
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
A556
Y
A
K
C
K
S
P
A
K
G
T
E
L
P
L
Chicken
Gallus gallus
O42400
841
94913
Y586
Y
A
T
K
S
R
N
Y
S
E
N
L
G
M
A
Frog
Xenopus laevis
Q9YGY0
842
94441
Y586
Y
A
T
K
S
R
N
Y
A
E
S
M
G
M
A
Zebra Danio
Brachydanio rerio
P57094
835
94310
Y587
Y
G
P
K
S
R
N
Y
A
D
G
M
S
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
V505
Q
D
I
L
D
Q
H
V
S
R
V
W
K
D
Q
Honey Bee
Apis mellifera
XP_001120373
693
78297
R457
G
H
D
Q
R
F
R
R
S
D
M
T
R
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
K544
H
K
K
R
S
S
K
K
S
D
I
S
S
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
N.A.
86.6
N.A.
87
84.2
N.A.
43.2
73
67.5
64
N.A.
21.8
27.2
N.A.
33
Protein Similarity:
100
95.1
N.A.
91.2
N.A.
91.1
88.1
N.A.
59.4
82.9
79.4
74.8
N.A.
38
42.4
N.A.
50.3
P-Site Identity:
100
100
N.A.
66.6
N.A.
13.3
13.3
N.A.
0
46.6
46.6
26.6
N.A.
6.6
6.6
N.A.
26.6
P-Site Similarity:
100
100
N.A.
80
N.A.
13.3
13.3
N.A.
13.3
73.3
73.3
60
N.A.
13.3
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
25
17
0
0
0
9
17
0
0
0
9
25
42
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
0
0
0
0
25
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
42
17
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
42
0
0
0
0
17
0
0
9
9
0
42
17
9
% G
% His:
50
9
17
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% I
% Lys:
0
9
17
34
25
0
9
9
9
0
0
0
9
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
17
0
17
0
% M
% Asn:
0
0
0
0
0
0
25
0
0
0
9
9
0
0
0
% N
% Pro:
0
0
9
0
9
17
9
0
0
0
0
0
0
9
0
% P
% Gln:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
25
9
50
25
9
0
9
0
0
9
9
0
% R
% Ser:
0
0
0
0
50
17
9
17
59
17
34
17
17
0
17
% S
% Thr:
0
9
17
0
0
0
0
0
0
0
9
9
9
0
17
% T
% Val:
0
0
0
0
0
0
0
9
0
0
9
25
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
34
0
0
0
0
0
0
42
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _