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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGRMC2
All Species:
16.67
Human Site:
S114
Identified Species:
28.21
UniProt:
O15173
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15173
NP_006311.1
223
23818
S114
Q
L
R
Q
Y
D
G
S
R
N
P
R
I
L
L
Chimpanzee
Pan troglodytes
XP_517434
247
26110
S138
Q
L
R
Q
Y
D
G
S
R
N
P
R
I
L
L
Rhesus Macaque
Macaca mulatta
XP_001082791
247
25994
S138
Q
L
R
Q
Y
D
G
S
R
N
P
R
I
L
L
Dog
Lupus familis
XP_533292
223
23762
S114
Q
L
R
Q
Y
D
G
S
R
T
P
R
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80UU9
217
23316
A108
Q
L
R
Q
Y
D
G
A
R
T
P
R
I
L
L
Rat
Rattus norvegicus
Q5XIU9
217
23385
A108
Q
L
R
Q
Y
D
G
A
R
T
P
R
I
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513451
172
18645
R66
R
P
R
G
G
V
E
R
A
G
L
G
R
R
E
Chicken
Gallus gallus
Q5ZKN2
192
21263
P85
P
Y
D
G
V
R
D
P
R
I
L
M
A
V
N
Frog
Xenopus laevis
NP_001089766
194
21749
P88
E
Y
D
G
T
H
N
P
R
I
L
L
A
V
N
Zebra Danio
Brachydanio rerio
NP_998269
201
22515
V92
Q
L
R
D
Y
D
G
V
Q
N
P
R
I
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573087
248
27902
T94
E
L
R
Q
Y
D
G
T
Q
P
D
G
R
V
L
Honey Bee
Apis mellifera
XP_396615
198
22142
L92
K
G
P
D
G
R
I
L
I
A
I
N
G
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783332
173
19917
N67
T
E
Y
D
G
I
K
N
E
G
R
I
L
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12091
152
16739
P46
V
V
A
G
N
F
F
P
R
T
L
S
K
F
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
88.6
95.9
N.A.
87.8
87.4
N.A.
48.8
55.1
66.8
63.2
N.A.
42.3
41.2
N.A.
45.7
Protein Similarity:
100
89.4
89
96.8
N.A.
89.6
89.2
N.A.
52.9
68.1
78.4
73.5
N.A.
56.8
60.5
N.A.
60.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
6.6
6.6
6.6
73.3
N.A.
46.6
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
13.3
13.3
20
86.6
N.A.
73.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
15
8
8
0
0
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
22
0
58
8
0
0
0
8
0
0
0
0
% D
% Glu:
15
8
0
0
0
0
8
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
29
22
0
58
0
0
15
0
15
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
8
15
8
8
50
0
0
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% K
% Leu:
0
58
0
0
0
0
0
8
0
0
29
8
8
50
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
8
0
8
8
0
29
0
8
0
0
22
% N
% Pro:
8
8
8
0
0
0
0
22
0
8
50
0
0
0
0
% P
% Gln:
50
0
0
50
0
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
8
0
65
0
0
15
0
8
65
0
8
50
15
8
0
% R
% Ser:
0
0
0
0
0
0
0
29
0
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
8
0
0
8
0
29
0
0
0
0
0
% T
% Val:
8
8
0
0
8
8
0
8
0
0
0
0
0
29
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
8
0
58
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _