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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGRMC2
All Species:
19.09
Human Site:
S19
Identified Species:
32.31
UniProt:
O15173
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15173
NP_006311.1
223
23818
S19
T
L
G
S
G
S
E
S
S
N
D
G
G
S
E
Chimpanzee
Pan troglodytes
XP_517434
247
26110
S43
T
L
G
S
G
S
E
S
S
N
D
G
G
S
E
Rhesus Macaque
Macaca mulatta
XP_001082791
247
25994
S43
T
L
G
S
G
S
E
S
S
S
D
G
G
S
E
Dog
Lupus familis
XP_533292
223
23762
S19
T
L
G
S
G
S
E
S
S
S
D
G
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80UU9
217
23316
S19
T
L
G
S
G
G
E
S
G
G
D
G
S
P
G
Rat
Rattus norvegicus
Q5XIU9
217
23385
R19
T
L
G
S
G
G
E
R
G
G
D
G
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513451
172
18645
Chicken
Gallus gallus
Q5ZKN2
192
21263
M8
M
A
A
E
E
P
A
M
A
G
E
E
A
V
A
Frog
Xenopus laevis
NP_001089766
194
21749
L11
S
L
E
V
E
E
L
L
A
G
T
S
P
P
G
Zebra Danio
Brachydanio rerio
NP_998269
201
22515
S15
R
S
A
V
A
D
T
S
G
D
Q
G
T
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573087
248
27902
E16
P
S
S
A
Y
D
K
E
I
G
N
N
L
N
N
Honey Bee
Apis mellifera
XP_396615
198
22142
T15
P
G
S
T
S
T
S
T
G
H
E
S
Q
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783332
173
19917
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12091
152
16739
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
88.6
95.9
N.A.
87.8
87.4
N.A.
48.8
55.1
66.8
63.2
N.A.
42.3
41.2
N.A.
45.7
Protein Similarity:
100
89.4
89
96.8
N.A.
89.6
89.2
N.A.
52.9
68.1
78.4
73.5
N.A.
56.8
60.5
N.A.
60.9
P-Site Identity:
100
100
93.3
86.6
N.A.
60
53.3
N.A.
0
0
6.6
20
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
60
53.3
N.A.
0
13.3
20
33.3
N.A.
26.6
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
8
8
0
8
0
15
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
0
0
8
43
0
0
0
0
% D
% Glu:
0
0
8
8
15
8
43
8
0
0
15
8
0
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
43
0
43
15
0
0
29
36
0
50
22
0
22
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
0
0
0
0
8
8
0
0
0
0
8
0
8
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
8
8
0
8
8
% N
% Pro:
15
0
0
0
0
8
0
0
0
0
0
0
8
29
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
15
15
43
8
29
8
43
29
15
0
15
22
29
0
% S
% Thr:
43
0
0
8
0
8
8
8
0
0
8
0
8
8
0
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _