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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
T
All Species:
6.06
Human Site:
S275
Identified Species:
13.33
UniProt:
O15178
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15178
NP_003172.1
435
47443
S275
L
S
L
P
S
T
H
S
C
D
R
Y
P
T
L
Chimpanzee
Pan troglodytes
XP_527563
464
50405
G304
L
S
L
P
S
T
H
G
C
D
R
Y
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001101514
435
47314
G275
L
S
L
P
S
T
H
G
C
D
R
Y
P
A
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P20293
436
47422
G275
L
S
L
P
S
T
H
G
C
E
R
Y
P
A
L
Rat
Rattus norvegicus
Q5I2P1
517
57726
Y353
P
S
E
E
D
T
F
Y
R
S
G
Y
P
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79777
433
47270
S274
L
S
L
S
P
A
H
S
C
E
R
Y
S
P
L
Frog
Xenopus laevis
P24781
432
47581
G273
L
S
L
S
S
P
H
G
C
E
R
Y
S
S
L
Zebra Danio
Brachydanio rerio
Q07998
423
45815
S264
F
N
G
A
P
V
H
S
S
G
S
Y
C
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55965
697
72099
G403
T
S
V
S
S
S
S
G
G
G
I
G
S
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
Q264
R
M
N
G
D
A
T
Q
S
P
P
G
K
T
A
Sea Urchin
Strong. purpuratus
XP_782140
502
53690
S342
A
S
S
M
P
A
C
S
Q
Y
G
S
M
W
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
98.1
N.A.
N.A.
91.2
30.3
N.A.
N.A.
80.2
74.7
62.5
N.A.
35.1
N.A.
31.4
47.2
Protein Similarity:
100
93.3
98.6
N.A.
N.A.
94.5
43.9
N.A.
N.A.
87.5
85
76.7
N.A.
46
N.A.
48.9
61.9
P-Site Identity:
100
86.6
86.6
N.A.
N.A.
80
26.6
N.A.
N.A.
60
60
20
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
86.6
86.6
N.A.
N.A.
86.6
26.6
N.A.
N.A.
66.6
73.3
26.6
N.A.
26.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
28
0
0
0
0
0
0
0
37
10
% A
% Cys:
0
0
0
0
0
0
10
0
55
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
19
0
0
0
0
28
0
0
0
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
0
28
0
0
0
10
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
46
10
19
19
19
0
0
0
% G
% His:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
55
0
55
0
0
0
0
0
0
0
0
0
0
0
55
% L
% Met:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
37
28
10
0
0
0
10
10
0
46
10
19
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
10
10
% Q
% Arg:
10
0
0
0
0
0
0
0
10
0
55
0
0
0
10
% R
% Ser:
0
82
10
28
55
10
10
37
19
10
10
10
28
10
0
% S
% Thr:
10
0
0
0
0
46
10
0
0
0
0
0
0
19
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
0
73
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _