KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
T
All Species:
17.88
Human Site:
S345
Identified Species:
39.33
UniProt:
O15178
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15178
NP_003172.1
435
47443
S345
A
S
P
P
T
S
S
S
Q
Y
P
S
L
W
S
Chimpanzee
Pan troglodytes
XP_527563
464
50405
S374
A
S
P
P
T
S
S
S
Q
Y
P
S
L
W
S
Rhesus Macaque
Macaca mulatta
XP_001101514
435
47314
S345
A
S
P
P
T
S
S
S
Q
Y
P
S
L
W
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P20293
436
47422
S345
A
S
P
P
T
G
S
S
Q
Y
P
S
L
W
S
Rat
Rattus norvegicus
Q5I2P1
517
57726
Q423
P
M
D
R
L
P
Y
Q
H
F
S
A
H
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79777
433
47270
S344
S
T
G
T
A
T
S
S
S
Q
Y
P
N
L
W
Frog
Xenopus laevis
P24781
432
47581
S343
S
T
G
T
P
P
P
S
S
Q
Y
P
S
L
W
Zebra Danio
Brachydanio rerio
Q07998
423
45815
N334
H
T
T
N
T
T
S
N
T
S
Q
Y
P
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55965
697
72099
S473
R
N
I
S
S
H
N
S
P
S
P
T
N
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
D334
F
C
I
P
P
P
I
D
M
M
Y
Q
N
M
P
Sea Urchin
Strong. purpuratus
XP_782140
502
53690
A412
T
T
A
N
S
S
E
A
H
A
L
S
Q
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
98.1
N.A.
N.A.
91.2
30.3
N.A.
N.A.
80.2
74.7
62.5
N.A.
35.1
N.A.
31.4
47.2
Protein Similarity:
100
93.3
98.6
N.A.
N.A.
94.5
43.9
N.A.
N.A.
87.5
85
76.7
N.A.
46
N.A.
48.9
61.9
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
N.A.
13.3
6.6
13.3
N.A.
20
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
26.6
N.A.
N.A.
33.3
20
33.3
N.A.
46.6
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
10
0
10
0
0
10
0
10
0
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
19
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
10
0
0
0
0
10
0
0
19
0
0
0
10
0
0
% H
% Ile:
0
0
19
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
10
0
37
19
10
% L
% Met:
0
10
0
0
0
0
0
0
10
10
0
0
0
10
0
% M
% Asn:
0
10
0
19
0
0
10
10
0
0
0
0
28
0
0
% N
% Pro:
10
0
37
46
19
28
10
0
10
0
46
19
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
37
19
10
10
10
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
37
0
10
19
37
55
64
19
19
10
46
10
19
46
% S
% Thr:
10
37
10
19
46
19
0
0
10
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
37
19
% W
% Tyr:
0
0
0
0
0
0
10
0
0
37
28
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _