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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: T All Species: 15.45
Human Site: S391 Identified Species: 34
UniProt: O15178 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15178 NP_003172.1 435 47443 S391 T P L T H P V S A P S S S G S
Chimpanzee Pan troglodytes XP_527563 464 50405 S420 T P L T H P V S A P S S S G S
Rhesus Macaque Macaca mulatta XP_001101514 435 47314 S391 A P L T H P V S A P S S S G S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P20293 436 47422 S391 T P L T H T V S A A T S S S S
Rat Rattus norvegicus Q5I2P1 517 57726 C469 H Q P V V R Q C G P Q T G L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P79777 433 47270 V390 Y T A L P H P V T A T T S T S
Frog Xenopus laevis P24781 432 47581 V389 Y S S L S H A V P S P S T G S
Zebra Danio Brachydanio rerio Q07998 423 45815 S380 M S Y S G L T S S L P V S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P55965 697 72099 G519 T G V G V G G G A G T T G S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 S380 K H L A K A S S E C K V E A T
Sea Urchin Strong. purpuratus XP_782140 502 53690 T458 D S Y H G D I T G S S V G L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 98.1 N.A. N.A. 91.2 30.3 N.A. N.A. 80.2 74.7 62.5 N.A. 35.1 N.A. 31.4 47.2
Protein Similarity: 100 93.3 98.6 N.A. N.A. 94.5 43.9 N.A. N.A. 87.5 85 76.7 N.A. 46 N.A. 48.9 61.9
P-Site Identity: 100 100 93.3 N.A. N.A. 73.3 6.6 N.A. N.A. 13.3 20 13.3 N.A. 13.3 N.A. 13.3 6.6
P-Site Similarity: 100 100 93.3 N.A. N.A. 80 13.3 N.A. N.A. 26.6 26.6 26.6 N.A. 33.3 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 0 10 10 0 46 19 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 19 10 10 10 19 10 0 0 28 37 0 % G
% His: 10 10 0 10 37 19 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 46 19 0 10 0 0 0 10 0 0 0 19 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 37 10 0 10 28 10 0 10 37 19 0 0 0 19 % P
% Gln: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 10 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 28 10 10 10 0 10 55 10 19 37 46 55 28 55 % S
% Thr: 37 10 0 37 0 10 10 10 10 0 28 28 10 10 10 % T
% Val: 0 0 10 10 19 0 37 19 0 0 0 28 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _