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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL
All Species:
19.39
Human Site:
S28
Identified Species:
35.56
UniProt:
O15194
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15194
NP_001008393.1
276
31129
S28
P
G
A
G
E
K
A
S
Q
C
N
V
S
L
K
Chimpanzee
Pan troglodytes
XP_516364
307
34324
S28
P
G
A
G
E
K
A
S
Q
C
N
V
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001086442
740
81182
S492
Q
L
G
L
E
G
T
S
Q
C
N
V
S
L
K
Dog
Lupus familis
XP_851254
347
38551
S80
Q
A
Q
C
T
G
A
S
Q
C
N
V
S
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P58465
276
31138
S28
P
V
A
G
E
K
A
S
Q
R
N
I
S
L
K
Rat
Rattus norvegicus
Q5XIK8
465
52764
K177
V
E
A
E
E
I
V
K
Q
L
D
M
E
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521318
361
40295
P114
E
K
A
R
A
T
V
P
Q
C
S
I
S
S
K
Chicken
Gallus gallus
Q9PTJ6
275
31225
S27
S
C
T
Q
D
K
V
S
Q
C
N
I
S
L
K
Frog
Xenopus laevis
Q801R4
466
52941
S97
P
R
T
G
D
K
P
S
K
P
I
A
R
V
R
Zebra Danio
Brachydanio rerio
A4QNX6
460
52428
E156
P
D
Q
V
V
E
A
E
E
I
V
K
Q
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
C22
L
L
S
K
V
W
T
C
I
C
F
M
F
N
R
Honey Bee
Apis mellifera
XP_623986
293
32413
A33
L
P
Q
E
N
E
V
A
N
N
S
P
A
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
R152
E
Y
N
V
D
A
D
R
N
S
S
I
N
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
36.4
74.6
N.A.
96
27.9
N.A.
63.9
88.7
28.1
28.9
N.A.
31.1
59
N.A.
N.A.
Protein Similarity:
100
89.9
37.1
77.2
N.A.
97.8
39.1
N.A.
68.4
93.4
39.2
39.7
N.A.
48.1
70.9
N.A.
N.A.
P-Site Identity:
100
100
60
60
N.A.
80
20
N.A.
33.3
53.3
26.6
20
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
60
60
N.A.
86.6
33.3
N.A.
46.6
66.6
53.3
40
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
39
0
8
8
39
8
0
0
0
8
8
0
0
% A
% Cys:
0
8
0
8
0
0
0
8
0
54
0
0
0
0
0
% C
% Asp:
0
8
0
0
24
0
8
0
0
0
8
0
0
8
0
% D
% Glu:
16
8
0
16
39
16
0
8
8
0
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
16
8
31
0
16
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
8
8
31
0
0
0
% I
% Lys:
0
8
0
8
0
39
0
8
8
0
0
8
0
0
54
% K
% Leu:
16
16
0
8
0
0
0
0
0
8
0
0
0
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
16
8
47
0
8
8
0
% N
% Pro:
39
8
0
0
0
0
8
8
0
8
0
8
0
0
0
% P
% Gln:
16
0
24
8
0
0
0
0
62
0
0
0
8
8
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
8
0
0
8
0
16
% R
% Ser:
8
0
8
0
0
0
0
54
0
8
24
0
54
16
0
% S
% Thr:
0
0
16
0
8
8
16
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
16
16
0
31
0
0
0
8
31
0
8
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _