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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL
All Species:
22.12
Human Site:
S41
Identified Species:
40.56
UniProt:
O15194
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15194
NP_001008393.1
276
31129
S41
L
K
K
Q
R
S
R
S
I
L
S
S
F
F
C
Chimpanzee
Pan troglodytes
XP_516364
307
34324
S41
L
K
K
Q
R
S
R
S
I
L
S
S
F
F
C
Rhesus Macaque
Macaca mulatta
XP_001086442
740
81182
S505
L
K
K
Q
R
S
R
S
I
L
S
S
F
F
C
Dog
Lupus familis
XP_851254
347
38551
G93
L
K
K
Q
R
S
R
G
I
L
S
S
F
F
C
Cat
Felis silvestris
Mouse
Mus musculus
P58465
276
31138
S41
L
K
K
E
R
G
R
S
I
L
S
S
F
F
C
Rat
Rattus norvegicus
Q5XIK8
465
52764
S190
Q
V
D
E
I
T
T
S
T
T
S
A
N
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521318
361
40295
S127
S
K
K
Q
R
R
R
S
I
F
S
S
L
F
C
Chicken
Gallus gallus
Q9PTJ6
275
31225
S40
L
K
K
Q
R
S
R
S
I
F
S
T
L
F
C
Frog
Xenopus laevis
Q801R4
466
52941
N110
V
R
R
K
S
Q
V
N
G
E
A
T
A
Y
E
Zebra Danio
Brachydanio rerio
A4QNX6
460
52428
E169
L
E
M
E
Q
V
E
E
M
P
T
C
T
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
I35
N
R
Q
V
R
A
F
I
Q
Y
Q
P
V
K
Y
Honey Bee
Apis mellifera
XP_623986
293
32413
R46
S
G
K
K
P
R
G
R
G
L
L
R
S
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
G165
D
E
A
P
P
Q
Q
G
L
Y
Q
V
G
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
36.4
74.6
N.A.
96
27.9
N.A.
63.9
88.7
28.1
28.9
N.A.
31.1
59
N.A.
N.A.
Protein Similarity:
100
89.9
37.1
77.2
N.A.
97.8
39.1
N.A.
68.4
93.4
39.2
39.7
N.A.
48.1
70.9
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
73.3
80
0
6.6
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
73.3
86.6
53.3
40
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
54
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
0
24
0
0
8
8
0
8
0
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
8
0
0
16
0
0
39
54
0
% F
% Gly:
0
8
0
0
0
8
8
16
16
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
54
0
0
0
0
0
0
% I
% Lys:
0
54
62
16
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
54
0
0
0
0
0
0
0
8
47
8
0
16
8
8
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
8
16
0
0
0
0
8
0
8
0
0
0
% P
% Gln:
8
0
8
47
8
16
8
0
8
0
16
0
0
8
0
% Q
% Arg:
0
16
8
0
62
16
54
8
0
0
0
8
0
0
0
% R
% Ser:
16
0
0
0
8
39
0
54
0
0
62
47
8
0
0
% S
% Thr:
0
0
0
0
0
8
8
0
8
8
8
16
8
0
8
% T
% Val:
8
8
0
8
0
8
8
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _