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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL
All Species:
35.15
Human Site:
T248
Identified Species:
64.44
UniProt:
O15194
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15194
NP_001008393.1
276
31129
T248
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Chimpanzee
Pan troglodytes
XP_516364
307
34324
T248
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Rhesus Macaque
Macaca mulatta
XP_001086442
740
81182
T712
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Dog
Lupus familis
XP_851254
347
38551
T319
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Cat
Felis silvestris
Mouse
Mus musculus
P58465
276
31138
T248
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Rat
Rattus norvegicus
Q5XIK8
465
52764
N429
W
F
M
D
K
N
D
N
E
L
L
K
L
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521318
361
40295
T334
W
F
D
D
M
T
D
T
E
L
L
D
L
L
P
Chicken
Gallus gallus
Q9PTJ6
275
31225
T247
W
F
D
D
M
T
D
T
E
L
L
D
L
I
P
Frog
Xenopus laevis
Q801R4
466
52941
K430
W
F
M
D
K
N
D
K
E
L
L
K
L
V
P
Zebra Danio
Brachydanio rerio
A4QNX6
460
52428
S424
W
F
M
D
R
N
D
S
E
L
L
K
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
L216
M
D
T
A
L
L
S
L
L
P
M
L
D
A
L
Honey Bee
Apis mellifera
XP_623986
293
32413
S243
W
F
D
D
M
T
D
S
E
L
L
D
L
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
N369
W
F
S
D
T
H
D
N
E
L
L
D
I
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
36.4
74.6
N.A.
96
27.9
N.A.
63.9
88.7
28.1
28.9
N.A.
31.1
59
N.A.
N.A.
Protein Similarity:
100
89.9
37.1
77.2
N.A.
97.8
39.1
N.A.
68.4
93.4
39.2
39.7
N.A.
48.1
70.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
66.6
N.A.
93.3
100
60
60
N.A.
0
93.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
100
100
66.6
73.3
N.A.
13.3
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
62
93
0
0
93
0
0
0
0
70
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% E
% Phe:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
70
0
% I
% Lys:
0
0
0
0
16
0
0
8
0
0
0
24
0
0
0
% K
% Leu:
0
0
0
0
8
8
0
8
8
93
93
8
85
8
8
% L
% Met:
8
0
24
0
62
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
24
0
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
93
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
16
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
8
62
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% V
% Trp:
93
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _