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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VILL
All Species:
18.48
Human Site:
T577
Identified Species:
45.19
UniProt:
O15195
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15195
NP_056957.3
856
95907
T577
I
S
R
K
N
E
E
T
V
L
E
G
Q
E
P
Chimpanzee
Pan troglodytes
XP_526028
827
92713
T576
M
A
K
M
V
A
D
T
I
S
R
T
E
K
Q
Rhesus Macaque
Macaca mulatta
XP_001090095
855
95936
T576
I
S
K
K
N
E
E
T
V
L
E
G
Q
E
P
Dog
Lupus familis
XP_542704
857
94887
T578
M
S
G
E
T
K
E
T
V
L
E
G
Q
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91YD6
859
96491
T577
F
P
G
N
N
K
E
T
V
L
E
G
Q
E
P
Rat
Rattus norvegicus
Q68FP1
780
86049
R523
G
G
T
P
V
Q
S
R
V
V
Q
G
K
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02640
826
92461
E566
G
K
G
C
S
G
D
E
R
E
M
G
K
M
V
Frog
Xenopus laevis
P14885
417
46006
P168
R
V
V
Q
G
K
E
P
A
H
L
I
S
L
F
Zebra Danio
Brachydanio rerio
XP_682946
850
94621
T582
L
S
G
Q
D
K
Q
T
V
M
E
G
Q
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81644
976
107824
E591
I
T
L
K
H
A
K
E
G
T
E
S
S
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.5
93.6
68.3
N.A.
72.2
34.7
N.A.
N.A.
45.9
21
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65.7
96.3
76.4
N.A.
82.5
49.7
N.A.
N.A.
66.2
32
66.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
66.6
N.A.
66.6
26.6
N.A.
N.A.
6.6
6.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
100
86.6
N.A.
73.3
53.3
N.A.
N.A.
26.6
20
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
20
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
20
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
20
50
20
0
10
60
0
10
60
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
20
10
40
0
10
10
0
0
10
0
0
70
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
30
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
10
20
30
0
40
10
0
0
0
0
0
20
10
0
% K
% Leu:
10
0
10
0
0
0
0
0
0
40
10
0
0
10
0
% L
% Met:
20
0
0
10
0
0
0
0
0
10
10
0
0
10
0
% M
% Asn:
0
0
0
10
30
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
60
% P
% Gln:
0
0
0
20
0
10
10
0
0
0
10
0
50
0
10
% Q
% Arg:
10
0
10
0
0
0
0
10
10
0
10
0
0
0
0
% R
% Ser:
0
40
0
0
10
0
10
0
0
10
0
10
20
0
0
% S
% Thr:
0
10
10
0
10
0
0
60
0
10
0
10
0
10
0
% T
% Val:
0
10
10
0
20
0
0
0
60
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _