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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMAD9
All Species:
30.3
Human Site:
Y279
Identified Species:
60.61
UniProt:
O15198
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15198
NP_001120689.1
467
52493
Y279
H
W
C
S
V
A
Y
Y
E
L
N
N
R
V
G
Chimpanzee
Pan troglodytes
XP_001144071
447
50421
R264
A
Y
Y
E
L
N
N
R
V
G
E
T
F
Q
A
Rhesus Macaque
Macaca mulatta
XP_001084638
467
52489
Y279
H
W
C
S
V
A
Y
Y
E
L
N
N
R
V
G
Dog
Lupus familis
XP_543131
469
52618
Y281
H
W
C
S
V
A
Y
Y
E
L
N
N
R
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIW5
430
48618
G249
Y
E
L
N
N
R
V
G
E
T
F
Q
A
S
S
Rat
Rattus norvegicus
O54835
434
48973
Q253
N
R
V
G
E
T
F
Q
A
S
S
R
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510776
466
52243
Y278
H
W
C
S
V
A
Y
Y
E
L
N
N
R
V
G
Chicken
Gallus gallus
Q56I99
465
52210
Y277
H
W
C
S
I
V
Y
Y
E
L
N
N
R
V
G
Frog
Xenopus laevis
NP_001079968
465
52655
Y277
H
W
C
S
V
A
Y
Y
E
L
N
N
R
V
G
Zebra Danio
Brachydanio rerio
Q9I8V2
472
53048
Y284
H
W
C
S
I
V
Y
Y
E
L
N
N
R
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42003
455
50486
Y267
F
W
A
S
I
A
Y
Y
E
L
N
C
R
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02330
418
47907
Q237
L
N
T
R
V
G
E
Q
V
K
V
S
S
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
99.7
95.7
N.A.
89.2
88.6
N.A.
92
79.2
86.7
78.5
N.A.
72.8
N.A.
51.6
N.A.
Protein Similarity:
100
84.8
100
96.8
N.A.
89.5
88.8
N.A.
94.8
86.7
92.2
86.8
N.A.
81.3
N.A.
63.5
N.A.
P-Site Identity:
100
0
100
100
N.A.
6.6
6.6
N.A.
100
86.6
100
86.6
N.A.
73.3
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
20
26.6
N.A.
100
93.3
100
93.3
N.A.
80
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
50
0
0
9
0
0
0
9
0
9
% A
% Cys:
0
0
59
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
9
9
0
9
0
75
0
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% F
% Gly:
0
0
0
9
0
9
0
9
0
9
0
0
0
0
67
% G
% His:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
9
0
9
0
9
0
0
0
0
67
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
9
9
9
9
0
0
0
67
59
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
9
0
9
0
% Q
% Arg:
0
9
0
9
0
9
0
9
0
0
0
9
67
0
0
% R
% Ser:
0
0
0
67
0
0
0
0
0
9
9
9
17
9
9
% S
% Thr:
0
0
9
0
0
9
0
0
0
9
0
9
0
9
9
% T
% Val:
0
0
9
0
50
17
9
0
17
0
9
0
0
75
0
% V
% Trp:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
9
0
0
0
67
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _