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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR46
All Species:
19.7
Human Site:
S528
Identified Species:
54.17
UniProt:
O15213
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15213
NP_005443.3
610
68041
S528
L
A
E
V
D
V
I
S
L
E
Q
G
K
K
E
Chimpanzee
Pan troglodytes
XP_518401
610
67957
S528
L
A
E
V
D
V
I
S
L
E
Q
G
K
K
E
Rhesus Macaque
Macaca mulatta
XP_001116143
616
68725
S531
L
A
E
V
D
V
I
S
L
E
Q
G
K
K
E
Dog
Lupus familis
XP_538859
599
66963
C516
K
V
P
A
E
L
I
C
L
D
P
R
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0H1
622
69030
T527
L
A
E
V
D
V
V
T
L
E
Q
Q
K
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087116
586
66355
T500
L
G
E
V
D
A
I
T
M
E
Q
K
H
K
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120711
531
60342
E458
L
L
Y
L
K
P
K
E
I
D
F
K
P
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790461
566
64787
T488
I
S
A
I
D
K
A
T
L
D
Q
R
Q
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40055
554
62298
N474
A
Q
T
T
M
D
A
N
N
K
A
K
T
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
83.6
N.A.
83.7
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
N.A.
N.A.
42.1
N.A.
47
Protein Similarity:
100
99.6
97.7
88.5
N.A.
88.9
N.A.
N.A.
N.A.
N.A.
69.8
N.A.
N.A.
N.A.
58.2
N.A.
65.2
P-Site Identity:
100
100
100
13.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
33.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
45
12
12
0
12
23
0
0
0
12
0
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
12
0
0
0
34
0
0
0
0
0
% D
% Glu:
0
0
56
0
12
0
0
12
0
56
0
0
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
12
0
0
12
0
0
56
0
12
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
12
12
12
0
0
12
0
34
45
56
0
% K
% Leu:
67
12
0
12
0
12
0
0
67
0
0
0
0
12
0
% L
% Met:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
12
0
0
0
0
12
0
% N
% Pro:
0
0
12
0
0
12
0
0
0
0
12
0
12
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
67
12
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
23
0
12
12
% R
% Ser:
0
12
0
0
0
0
0
34
0
0
0
0
0
0
12
% S
% Thr:
0
0
12
12
0
0
0
34
0
0
0
0
12
0
0
% T
% Val:
0
12
0
56
0
45
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _