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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR46
All Species:
7.58
Human Site:
S584
Identified Species:
20.83
UniProt:
O15213
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15213
NP_005443.3
610
68041
S584
H
R
D
K
V
R
Q
S
L
Q
Q
Q
H
H
K
Chimpanzee
Pan troglodytes
XP_518401
610
67957
S584
H
R
D
K
V
R
Q
S
L
Q
Q
Q
H
H
K
Rhesus Macaque
Macaca mulatta
XP_001116143
616
68725
Q590
K
V
R
Q
S
L
Q
Q
Q
Q
Q
Q
Q
Q
K
Dog
Lupus familis
XP_538859
599
66963
L566
G
R
I
L
K
K
T
L
L
K
G
G
G
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0H1
622
69030
E585
D
K
V
R
Q
S
L
E
Q
Q
Q
Q
K
K
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087116
586
66355
S556
Q
R
E
H
V
R
K
S
M
E
V
R
E
K
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120711
531
60342
K506
A
N
I
Q
S
N
I
K
K
V
E
K
P
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790461
566
64787
Q540
E
G
N
R
D
K
I
Q
E
T
S
K
A
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40055
554
62298
N525
K
Q
L
D
K
E
K
N
I
R
K
R
N
H
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
83.6
N.A.
83.7
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
N.A.
N.A.
42.1
N.A.
47
Protein Similarity:
100
99.6
97.7
88.5
N.A.
88.9
N.A.
N.A.
N.A.
N.A.
69.8
N.A.
N.A.
N.A.
58.2
N.A.
65.2
P-Site Identity:
100
100
33.3
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
40
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
23
12
12
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
12
0
0
12
0
12
12
12
12
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
12
12
0
0
0
0
0
0
0
0
12
12
12
0
0
% G
% His:
23
0
0
12
0
0
0
0
0
0
0
0
23
34
0
% H
% Ile:
0
0
23
0
0
0
23
0
12
0
0
0
0
0
0
% I
% Lys:
23
12
0
23
23
23
23
12
12
12
12
23
12
23
56
% K
% Leu:
0
0
12
12
0
12
12
12
34
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
12
12
0
0
12
0
12
0
0
0
0
12
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
12
12
0
23
12
0
34
23
23
45
45
45
12
23
34
% Q
% Arg:
0
45
12
23
0
34
0
0
0
12
0
23
0
0
0
% R
% Ser:
0
0
0
0
23
12
0
34
0
0
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% T
% Val:
0
12
12
0
34
0
0
0
0
12
12
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _