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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR46
All Species:
16.36
Human Site:
S70
Identified Species:
45
UniProt:
O15213
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15213
NP_005443.3
610
68041
S70
I
L
K
K
S
R
I
S
K
K
P
Q
V
P
K
Chimpanzee
Pan troglodytes
XP_518401
610
67957
S70
I
L
K
K
S
R
I
S
K
K
P
Q
V
P
K
Rhesus Macaque
Macaca mulatta
XP_001116143
616
68725
S73
I
L
K
K
S
R
I
S
K
Q
P
Q
V
P
K
Dog
Lupus familis
XP_538859
599
66963
P71
L
P
K
K
S
R
I
P
G
K
P
Q
F
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0H1
622
69030
S71
I
A
Q
K
S
R
F
S
K
K
P
P
I
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087116
586
66355
K63
K
R
D
Q
K
K
P
K
S
K
F
I
S
G
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120711
531
60342
T64
K
Y
N
K
V
K
D
T
A
R
T
E
L
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790461
566
64787
F62
L
R
D
E
S
D
P
F
P
G
P
A
P
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40055
554
62298
Y73
L
L
P
E
S
N
G
Y
L
E
P
E
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.5
83.6
N.A.
83.7
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
N.A.
N.A.
42.1
N.A.
47
Protein Similarity:
100
99.6
97.7
88.5
N.A.
88.9
N.A.
N.A.
N.A.
N.A.
69.8
N.A.
N.A.
N.A.
58.2
N.A.
65.2
P-Site Identity:
100
100
93.3
66.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
12
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
12
12
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
23
0
0
0
0
0
12
0
23
0
12
0
% E
% Phe:
0
0
0
0
0
0
12
12
0
0
12
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
12
12
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
45
0
0
0
0
0
45
0
0
0
0
12
12
0
0
% I
% Lys:
23
0
45
67
12
23
0
12
45
56
0
0
0
0
56
% K
% Leu:
34
45
0
0
0
0
0
0
12
0
0
0
12
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
12
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
12
12
0
0
0
23
12
12
0
78
12
12
45
0
% P
% Gln:
0
0
12
12
0
0
0
0
0
12
0
45
0
0
0
% Q
% Arg:
0
23
0
0
0
56
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
0
78
0
0
45
12
0
0
0
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
0
34
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _