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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR46 All Species: 17.88
Human Site: T467 Identified Species: 49.17
UniProt: O15213 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15213 NP_005443.3 610 68041 T467 D V L G V G H T G G I T S M L
Chimpanzee Pan troglodytes XP_518401 610 67957 T467 D V L G V G H T G G I T S M L
Rhesus Macaque Macaca mulatta XP_001116143 616 68725 S470 D V L G V G H S G G V T S M L
Dog Lupus familis XP_538859 599 66963 S468 D V L G L G H S G G I T S M L
Cat Felis silvestris
Mouse Mus musculus Q9Z0H1 622 69030 S466 D V L G V G H S G G F T S M L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001087116 586 66355 G439 D V L G I G H G G G F T S M I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120711 531 60342 L418 E A E V K A L L D K I Q P E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790461 566 64787 F427 D V L G V S H F Q G Y S S L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40055 554 62298 L434 E Q E V R T L L N K L P A D T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.5 83.6 N.A. 83.7 N.A. N.A. N.A. N.A. 53.2 N.A. N.A. N.A. 42.1 N.A. 47
Protein Similarity: 100 99.6 97.7 88.5 N.A. 88.9 N.A. N.A. N.A. N.A. 69.8 N.A. N.A. N.A. 58.2 N.A. 65.2
P-Site Identity: 100 100 86.6 86.6 N.A. 86.6 N.A. N.A. N.A. N.A. 73.3 N.A. N.A. N.A. 13.3 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 86.6 N.A. N.A. N.A. 20 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 12 0 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 78 0 0 0 0 0 0 0 12 0 0 0 0 12 0 % D
% Glu: 23 0 23 0 0 0 0 0 0 0 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 23 0 0 0 0 % F
% Gly: 0 0 0 78 0 67 0 12 67 78 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 0 0 0 45 0 0 0 12 % I
% Lys: 0 0 0 0 12 0 0 0 0 23 0 0 0 0 0 % K
% Leu: 0 0 78 0 12 0 23 23 0 0 12 0 0 12 78 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % P
% Gln: 0 12 0 0 0 0 0 0 12 0 0 12 0 0 0 % Q
% Arg: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 12 0 34 0 0 0 12 78 0 0 % S
% Thr: 0 0 0 0 0 12 0 23 0 0 0 67 0 0 12 % T
% Val: 0 78 0 23 56 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _