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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNPAT All Species: 17.88
Human Site: S343 Identified Species: 32.78
UniProt: O15228 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15228 NP_055051.1 680 77188 S343 S L A A G R M S R S S Y N L V
Chimpanzee Pan troglodytes XP_001151001 680 77266 S343 S L A A G R M S R S S Y N L V
Rhesus Macaque Macaca mulatta XP_001106100 681 77392 S344 S L A A G R M S R S S Y N L V
Dog Lupus familis XP_536346 796 89554 S343 S L A A G R M S R N P Y N L V
Cat Felis silvestris
Mouse Mus musculus P98192 678 76851 N342 S L A A G R L N R N T Y N L V
Rat Rattus norvegicus Q9ES71 678 77057 S342 S L A A G R L S R N T Y N L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515438 468 51003 E163 R P G R R V P E G R G L T P P
Chicken Gallus gallus XP_419589 666 75764 N328 T L A S G R I N L C P Y N L V
Frog Xenopus laevis NP_001086144 664 75877 N326 S L S S G I I N R A Q F N L K
Zebra Danio Brachydanio rerio XP_701136 668 75935 N328 S L A E R K I N R S Q Y N L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525010 724 82506 A342 E F F G H D S A Q R M Q R A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496725 671 76767 H329 D H F G V S L H R N T F V C Q
Sea Urchin Strong. purpuratus XP_795518 672 76192 R317 D Q M K S I D R S R H N L I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.5 76.8 N.A. 81 81.4 N.A. 34.4 64.5 56 55.2 N.A. 28.7 N.A. 30.4 36.3
Protein Similarity: 100 99.7 98.9 81.4 N.A. 91.6 90.8 N.A. 44.5 81.4 74.4 74.2 N.A. 48.4 N.A. 51 58.6
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. 0 53.3 40 53.3 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 0 80 80 80 N.A. 13.3 N.A. 33.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 62 47 0 0 0 8 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % C
% Asp: 16 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 8 16 0 0 0 0 0 0 0 0 16 0 0 0 % F
% Gly: 0 0 8 16 62 0 0 0 8 0 8 0 0 0 8 % G
% His: 0 8 0 0 8 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 24 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 8 % K
% Leu: 0 70 0 0 0 0 24 0 8 0 0 8 8 70 8 % L
% Met: 0 0 8 0 0 0 31 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 31 0 31 0 8 70 0 0 % N
% Pro: 0 8 0 0 0 0 8 0 0 0 16 0 0 8 16 % P
% Gln: 0 8 0 0 0 0 0 0 8 0 16 8 0 0 8 % Q
% Arg: 8 0 0 8 16 54 0 8 70 24 0 0 8 0 0 % R
% Ser: 62 0 8 16 8 8 8 39 8 31 24 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 0 0 0 24 0 8 0 0 % T
% Val: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 54 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 62 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _