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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNPAT All Species: 12.73
Human Site: S345 Identified Species: 23.33
UniProt: O15228 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15228 NP_055051.1 680 77188 S345 A A G R M S R S S Y N L V P R
Chimpanzee Pan troglodytes XP_001151001 680 77266 S345 A A G R M S R S S Y N L V P R
Rhesus Macaque Macaca mulatta XP_001106100 681 77392 S346 A A G R M S R S S Y N L V P R
Dog Lupus familis XP_536346 796 89554 N345 A A G R M S R N P Y N L V P R
Cat Felis silvestris
Mouse Mus musculus P98192 678 76851 N344 A A G R L N R N T Y N L V P R
Rat Rattus norvegicus Q9ES71 678 77057 N344 A A G R L S R N T Y N L V P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515438 468 51003 R165 G R R V P E G R G L T P P A M
Chicken Gallus gallus XP_419589 666 75764 C330 A S G R I N L C P Y N L V P R
Frog Xenopus laevis NP_001086144 664 75877 A328 S S G I I N R A Q F N L K P R
Zebra Danio Brachydanio rerio XP_701136 668 75935 S330 A E R K I N R S Q Y N L L P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525010 724 82506 R344 F G H D S A Q R M Q R A G V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496725 671 76767 N331 F G V S L H R N T F V C Q P D
Sea Urchin Strong. purpuratus XP_795518 672 76192 R319 M K S I D R S R H N L I P R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.5 76.8 N.A. 81 81.4 N.A. 34.4 64.5 56 55.2 N.A. 28.7 N.A. 30.4 36.3
Protein Similarity: 100 99.7 98.9 81.4 N.A. 91.6 90.8 N.A. 44.5 81.4 74.4 74.2 N.A. 48.4 N.A. 51 58.6
P-Site Identity: 100 100 100 86.6 N.A. 73.3 80 N.A. 0 60 40 53.3 N.A. 0 N.A. 13.3 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 0 80 80 80 N.A. 13.3 N.A. 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 62 47 0 0 0 8 0 8 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 16 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % F
% Gly: 8 16 62 0 0 0 8 0 8 0 0 0 8 0 8 % G
% His: 0 0 8 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 24 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 24 0 8 0 0 8 8 70 8 0 0 % L
% Met: 8 0 0 0 31 0 0 0 8 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 31 0 31 0 8 70 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 16 0 0 8 16 77 0 % P
% Gln: 0 0 0 0 0 0 8 0 16 8 0 0 8 0 0 % Q
% Arg: 0 8 16 54 0 8 70 24 0 0 8 0 0 8 70 % R
% Ser: 8 16 8 8 8 39 8 31 24 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 24 0 8 0 0 0 0 % T
% Val: 0 0 8 8 0 0 0 0 0 0 8 0 54 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _