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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPAT
All Species:
34.55
Human Site:
T291
Identified Species:
63.33
UniProt:
O15228
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15228
NP_055051.1
680
77188
T291
Y
D
K
I
L
E
E
T
L
Y
V
Y
E
L
L
Chimpanzee
Pan troglodytes
XP_001151001
680
77266
T291
Y
D
K
I
L
E
E
T
L
Y
V
Y
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001106100
681
77392
T292
Y
D
K
I
L
E
E
T
L
Y
V
Y
E
L
L
Dog
Lupus familis
XP_536346
796
89554
T291
Y
D
K
I
L
E
E
T
L
Y
V
Y
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P98192
678
76851
S290
Y
D
K
I
L
E
E
S
L
Y
A
Y
E
I
L
Rat
Rattus norvegicus
Q9ES71
678
77057
S290
Y
D
K
I
L
E
E
S
L
Y
A
Y
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515438
468
51003
G111
T
A
A
R
A
P
A
G
S
G
A
L
H
R
A
Chicken
Gallus gallus
XP_419589
666
75764
S276
Y
E
R
I
L
E
E
S
L
Y
A
Y
E
L
L
Frog
Xenopus laevis
NP_001086144
664
75877
S274
Y
E
R
V
L
E
E
S
L
Y
A
F
E
L
L
Zebra Danio
Brachydanio rerio
XP_701136
668
75935
S276
Y
E
R
I
L
E
E
S
L
Y
A
R
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525010
724
82506
Q290
Y
E
R
V
L
E
E
Q
L
F
V
Y
E
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496725
671
76767
K277
Y
D
K
I
L
E
E
K
L
Y
A
Y
E
L
L
Sea Urchin
Strong. purpuratus
XP_795518
672
76192
K265
Y
E
R
I
V
E
E
K
L
H
A
Q
E
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
76.8
N.A.
81
81.4
N.A.
34.4
64.5
56
55.2
N.A.
28.7
N.A.
30.4
36.3
Protein Similarity:
100
99.7
98.9
81.4
N.A.
91.6
90.8
N.A.
44.5
81.4
74.4
74.2
N.A.
48.4
N.A.
51
58.6
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
0
73.3
60
66.6
N.A.
66.6
N.A.
86.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
93.3
93.3
86.6
N.A.
93.3
N.A.
86.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
0
8
0
0
0
62
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
39
0
0
0
93
93
0
0
0
0
0
93
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
77
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
54
0
0
0
0
16
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
85
0
0
0
93
0
0
8
0
77
93
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
39
8
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
39
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% T
% Val:
0
0
0
16
8
0
0
0
0
0
39
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
0
0
0
0
0
0
0
0
77
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _