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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPAT
All Species:
22.42
Human Site:
T616
Identified Species:
41.11
UniProt:
O15228
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15228
NP_055051.1
680
77188
T616
S
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
Chimpanzee
Pan troglodytes
XP_001151001
680
77266
T616
S
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001106100
681
77392
T617
S
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
Dog
Lupus familis
XP_536346
796
89554
T616
N
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P98192
678
76851
S615
Q
L
L
D
Q
G
S
S
Q
C
Y
D
A
L
S
Rat
Rattus norvegicus
Q9ES71
678
77057
S615
Q
L
L
D
Q
D
A
S
Q
C
Y
D
A
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515438
468
51003
A424
T
Y
N
T
D
R
E
A
V
A
K
V
E
G
M
Chicken
Gallus gallus
XP_419589
666
75764
T602
F
Q
L
L
E
K
G
T
T
Q
C
Y
E
A
L
Frog
Xenopus laevis
NP_001086144
664
75877
T600
S
R
Q
I
V
S
G
T
S
T
C
Y
E
A
L
Zebra Danio
Brachydanio rerio
XP_701136
668
75935
R604
L
K
L
I
L
G
G
R
L
T
C
F
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525010
724
82506
G642
E
Q
L
L
Q
Q
P
G
A
S
A
S
H
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496725
671
76767
P612
E
A
Y
Q
D
R
L
P
N
I
R
L
S
F
L
Sea Urchin
Strong. purpuratus
XP_795518
672
76192
Q595
R
I
A
T
I
I
S
Q
G
K
L
H
H
Y
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
76.8
N.A.
81
81.4
N.A.
34.4
64.5
56
55.2
N.A.
28.7
N.A.
30.4
36.3
Protein Similarity:
100
99.7
98.9
81.4
N.A.
91.6
90.8
N.A.
44.5
81.4
74.4
74.2
N.A.
48.4
N.A.
51
58.6
P-Site Identity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
6.6
60
46.6
33.3
N.A.
33.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
33.3
86.6
66.6
60
N.A.
40
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
8
8
8
8
8
0
16
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
54
0
0
0
0
% C
% Asp:
0
0
0
16
47
8
0
0
0
0
0
16
31
0
0
% D
% Glu:
16
0
0
0
8
0
8
0
0
0
0
0
31
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
0
0
16
54
8
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
16
0
8
% H
% Ile:
0
8
0
16
8
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
8
8
0
0
0
0
% K
% Leu:
8
16
70
47
8
0
8
0
8
0
8
8
0
16
62
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
16
47
8
8
24
39
0
8
16
39
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
16
0
8
0
0
8
0
0
0
0
% R
% Ser:
31
0
0
0
0
8
16
16
39
8
0
8
8
0
16
% S
% Thr:
8
0
0
16
0
0
0
47
8
16
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
8
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
16
47
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _