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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNPAT All Species: 29.39
Human Site: Y347 Identified Species: 53.89
UniProt: O15228 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15228 NP_055051.1 680 77188 Y347 G R M S R S S Y N L V P R Y I
Chimpanzee Pan troglodytes XP_001151001 680 77266 Y347 G R M S R S S Y N L V P R Y I
Rhesus Macaque Macaca mulatta XP_001106100 681 77392 Y348 G R M S R S S Y N L V P R Y I
Dog Lupus familis XP_536346 796 89554 Y347 G R M S R N P Y N L V P R Y I
Cat Felis silvestris
Mouse Mus musculus P98192 678 76851 Y346 G R L N R N T Y N L V P R C I
Rat Rattus norvegicus Q9ES71 678 77057 Y346 G R L S R N T Y N L V P R C I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515438 468 51003 L167 R V P E G R G L T P P A M F S
Chicken Gallus gallus XP_419589 666 75764 Y332 G R I N L C P Y N L V P R H L
Frog Xenopus laevis NP_001086144 664 75877 F330 G I I N R A Q F N L K P R H L
Zebra Danio Brachydanio rerio XP_701136 668 75935 Y332 R K I N R S Q Y N L L P R H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525010 724 82506 Q346 H D S A Q R M Q R A G V G G H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496725 671 76767 F333 V S L H R N T F V C Q P D S Q
Sea Urchin Strong. purpuratus XP_795518 672 76192 N321 S I D R S R H N L I P R F I F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.5 76.8 N.A. 81 81.4 N.A. 34.4 64.5 56 55.2 N.A. 28.7 N.A. 30.4 36.3
Protein Similarity: 100 99.7 98.9 81.4 N.A. 91.6 90.8 N.A. 44.5 81.4 74.4 74.2 N.A. 48.4 N.A. 51 58.6
P-Site Identity: 100 100 100 86.6 N.A. 66.6 73.3 N.A. 0 53.3 40 53.3 N.A. 0 N.A. 13.3 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 80 80 86.6 N.A. 13.3 N.A. 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 8 0 0 0 16 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 8 8 8 % F
% Gly: 62 0 0 0 8 0 8 0 0 0 8 0 8 8 0 % G
% His: 8 0 0 8 0 0 8 0 0 0 0 0 0 24 8 % H
% Ile: 0 16 24 0 0 0 0 0 0 8 0 0 0 8 54 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 24 0 8 0 0 8 8 70 8 0 0 0 16 % L
% Met: 0 0 31 0 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 31 0 31 0 8 70 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 16 0 0 8 16 77 0 0 0 % P
% Gln: 0 0 0 0 8 0 16 8 0 0 8 0 0 0 8 % Q
% Arg: 16 54 0 8 70 24 0 0 8 0 0 8 70 0 0 % R
% Ser: 8 8 8 39 8 31 24 0 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 0 0 24 0 8 0 0 0 0 0 0 % T
% Val: 8 8 0 0 0 0 0 0 8 0 54 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 0 0 0 0 0 31 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _