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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPAT
All Species:
28.79
Human Site:
Y586
Identified Species:
52.78
UniProt:
O15228
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15228
NP_055051.1
680
77188
Y586
S
Y
Q
I
I
C
K
Y
L
L
S
E
E
E
D
Chimpanzee
Pan troglodytes
XP_001151001
680
77266
Y586
S
Y
Q
I
I
C
K
Y
L
L
S
E
E
E
D
Rhesus Macaque
Macaca mulatta
XP_001106100
681
77392
Y587
S
Y
Q
I
I
C
K
Y
L
L
S
E
E
E
D
Dog
Lupus familis
XP_536346
796
89554
Y586
C
Y
Q
I
I
C
K
Y
L
L
N
E
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
P98192
678
76851
Y585
S
Y
Q
L
L
C
R
Y
L
L
H
E
E
D
Y
Rat
Rattus norvegicus
Q9ES71
678
77057
C585
S
Y
Q
I
L
S
K
C
L
L
H
E
E
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515438
468
51003
Q394
E
A
L
S
S
D
L
Q
K
N
A
L
A
A
L
Chicken
Gallus gallus
XP_419589
666
75764
Y572
G
Y
Q
L
I
F
R
Y
L
S
K
E
T
K
E
Frog
Xenopus laevis
NP_001086144
664
75877
Y570
G
Y
K
L
A
C
T
Y
L
L
G
E
V
T
N
Zebra Danio
Brachydanio rerio
XP_701136
668
75935
Y574
G
Y
Q
V
V
C
R
Y
L
C
E
E
T
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525010
724
82506
L612
Y
Y
Q
L
V
V
T
L
R
K
I
P
L
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496725
671
76767
F582
F
E
I
A
F
N
V
F
S
E
K
K
P
M
V
Sea Urchin
Strong. purpuratus
XP_795518
672
76192
Y565
G
Y
W
L
V
C
Q
Y
L
M
A
H
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
76.8
N.A.
81
81.4
N.A.
34.4
64.5
56
55.2
N.A.
28.7
N.A.
30.4
36.3
Protein Similarity:
100
99.7
98.9
81.4
N.A.
91.6
90.8
N.A.
44.5
81.4
74.4
74.2
N.A.
48.4
N.A.
51
58.6
P-Site Identity:
100
100
100
80
N.A.
60
60
N.A.
0
40
40
40
N.A.
20
N.A.
0
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
6.6
66.6
60
66.6
N.A.
33.3
N.A.
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
0
0
0
16
0
8
8
0
% A
% Cys:
8
0
0
0
0
62
0
8
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
24
31
% D
% Glu:
8
8
0
0
0
0
0
0
0
8
8
70
47
31
16
% E
% Phe:
8
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
31
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% H
% Ile:
0
0
8
39
39
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
39
0
8
8
16
8
0
8
0
% K
% Leu:
0
0
8
39
16
0
8
8
77
54
0
8
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
8
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
16
0
0
% P
% Gln:
0
0
70
0
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
24
0
8
0
0
0
0
0
0
% R
% Ser:
39
0
0
8
8
8
0
0
8
8
24
0
0
8
8
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
0
16
8
0
% T
% Val:
0
0
0
8
24
8
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
85
0
0
0
0
0
70
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _