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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPAT
All Species:
17.27
Human Site:
Y600
Identified Species:
31.67
UniProt:
O15228
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15228
NP_055051.1
680
77188
Y600
D
H
F
S
E
E
Q
Y
L
A
A
V
R
K
F
Chimpanzee
Pan troglodytes
XP_001151001
680
77266
Y600
D
H
F
S
E
E
Q
Y
L
A
A
V
R
K
F
Rhesus Macaque
Macaca mulatta
XP_001106100
681
77392
Y601
D
H
F
S
E
E
Q
Y
L
A
A
V
R
K
F
Dog
Lupus familis
XP_536346
796
89554
Y600
D
N
F
T
E
K
Q
Y
L
A
G
V
R
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P98192
678
76851
L599
Y
F
G
E
K
E
Y
L
V
A
A
R
K
F
T
Rat
Rattus norvegicus
Q9ES71
678
77057
L599
Y
F
S
E
K
E
Y
L
V
T
A
R
K
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515438
468
51003
S408
L
V
R
L
G
A
V
S
K
S
R
T
A
S
G
Chicken
Gallus gallus
XP_419589
666
75764
F586
E
A
F
T
E
K
Q
F
I
P
G
V
R
N
Y
Frog
Xenopus laevis
NP_001086144
664
75877
Y584
N
A
F
T
E
K
Q
Y
I
S
G
V
R
S
F
Zebra Danio
Brachydanio rerio
XP_701136
668
75935
F588
E
N
L
T
E
K
E
F
I
P
G
V
R
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525010
724
82506
L626
L
E
F
S
N
K
E
L
L
V
R
V
Q
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496725
671
76767
V596
V
S
S
L
S
E
M
V
G
T
V
Q
K
N
I
Sea Urchin
Strong. purpuratus
XP_795518
672
76192
K579
S
P
Q
G
V
P
I
K
Q
T
A
K
A
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
76.8
N.A.
81
81.4
N.A.
34.4
64.5
56
55.2
N.A.
28.7
N.A.
30.4
36.3
Protein Similarity:
100
99.7
98.9
81.4
N.A.
91.6
90.8
N.A.
44.5
81.4
74.4
74.2
N.A.
48.4
N.A.
51
58.6
P-Site Identity:
100
100
100
73.3
N.A.
20
13.3
N.A.
0
33.3
46.6
26.6
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
40
33.3
N.A.
6.6
73.3
80
73.3
N.A.
53.3
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
8
0
0
0
39
47
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
16
8
0
16
54
47
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
16
54
0
0
0
0
16
0
0
0
0
0
16
47
% F
% Gly:
0
0
8
8
8
0
0
0
8
0
31
0
0
0
8
% G
% His:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
24
0
0
0
0
8
8
% I
% Lys:
0
0
0
0
16
39
0
8
8
0
0
8
24
31
0
% K
% Leu:
16
0
8
16
0
0
0
24
39
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
16
0
0
8
0
0
0
0
0
0
0
0
16
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
16
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
47
0
8
0
0
8
8
8
8
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
16
16
54
0
0
% R
% Ser:
8
8
16
31
8
0
0
8
0
16
0
0
0
16
0
% S
% Thr:
0
0
0
31
0
0
0
0
0
24
0
8
0
0
16
% T
% Val:
8
8
0
0
8
0
8
8
16
8
8
62
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
16
39
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _