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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPAT
All Species:
22.12
Human Site:
Y620
Identified Species:
40.56
UniProt:
O15228
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15228
NP_055051.1
680
77188
Y620
D
Q
G
T
S
Q
C
Y
D
V
L
S
S
D
V
Chimpanzee
Pan troglodytes
XP_001151001
680
77266
Y620
D
Q
G
T
S
Q
C
Y
D
V
L
S
S
D
V
Rhesus Macaque
Macaca mulatta
XP_001106100
681
77392
Y621
D
Q
G
T
S
Q
C
Y
D
V
L
S
S
D
V
Dog
Lupus familis
XP_536346
796
89554
Y620
D
Q
G
T
S
Q
C
Y
D
V
L
S
C
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P98192
678
76851
D619
Q
G
S
S
Q
C
Y
D
A
L
S
S
E
L
Q
Rat
Rattus norvegicus
Q9ES71
678
77057
D619
Q
D
A
S
Q
C
Y
D
A
L
S
S
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515438
468
51003
V428
D
R
E
A
V
A
K
V
E
G
M
L
G
K
A
Chicken
Gallus gallus
XP_419589
666
75764
Y606
E
K
G
T
T
Q
C
Y
E
A
L
S
S
D
M
Frog
Xenopus laevis
NP_001086144
664
75877
Y604
V
S
G
T
S
T
C
Y
E
A
L
S
S
D
M
Zebra Danio
Brachydanio rerio
XP_701136
668
75935
F608
L
G
G
R
L
T
C
F
E
V
L
S
S
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_525010
724
82506
S646
Q
Q
P
G
A
S
A
S
H
V
H
P
Y
C
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496725
671
76767
L616
D
R
L
P
N
I
R
L
S
F
L
S
T
E
P
Sea Urchin
Strong. purpuratus
XP_795518
672
76192
H599
I
I
S
Q
G
K
L
H
H
Y
E
I
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
76.8
N.A.
81
81.4
N.A.
34.4
64.5
56
55.2
N.A.
28.7
N.A.
30.4
36.3
Protein Similarity:
100
99.7
98.9
81.4
N.A.
91.6
90.8
N.A.
44.5
81.4
74.4
74.2
N.A.
48.4
N.A.
51
58.6
P-Site Identity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
6.6
60
60
46.6
N.A.
13.3
N.A.
20
0
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
26.6
93.3
73.3
66.6
N.A.
26.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
8
8
0
16
16
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
16
54
0
0
0
0
0
8
8
0
% C
% Asp:
47
8
0
0
0
0
0
16
31
0
0
0
0
54
0
% D
% Glu:
8
0
8
0
0
0
0
0
31
0
8
0
16
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
16
54
8
8
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
16
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
0
0
8
8
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
8
0
8
0
8
8
0
16
62
8
8
16
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
24
39
0
8
16
39
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
16
0
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
16
16
39
8
0
8
8
0
16
77
47
8
0
% S
% Thr:
0
0
0
47
8
16
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
8
0
0
8
0
47
0
0
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
47
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _