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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
4.55
Human Site:
S335
Identified Species:
7.14
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
S335
D
E
L
M
D
K
F
S
N
D
L
S
L
C
L
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
S335
D
E
L
M
D
K
F
S
N
D
L
S
L
C
L
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
G314
H
A
I
V
P
F
F
G
Q
G
M
N
A
G
F
Dog
Lupus familis
XP_537216
492
56859
N350
D
E
L
M
D
K
F
N
N
D
F
S
M
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
N335
D
E
L
M
D
K
F
N
N
N
L
S
M
C
L
Rat
Rattus norvegicus
O88867
478
54335
N335
D
E
L
M
D
K
F
N
N
D
L
S
V
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
G314
H
A
I
V
P
F
F
G
Q
G
M
N
A
G
F
Chicken
Gallus gallus
XP_421897
486
55752
H345
D
E
L
M
D
Q
F
H
N
D
L
G
A
C
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
F329
G
Q
G
M
N
A
G
F
E
D
C
L
V
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
G324
A
D
K
A
L
I
L
G
D
A
A
H
A
M
V
Honey Bee
Apis mellifera
XP_624246
454
52385
A316
H
A
M
V
P
F
Y
A
Q
G
M
N
T
G
F
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
A316
N
L
V
L
M
G
D
A
A
H
A
M
V
P
F
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
F326
G
Q
G
M
N
C
G
F
E
D
C
L
V
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
P305
N
C
K
P
Y
D
V
P
G
G
K
A
I
L
L
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
A368
N
D
D
S
S
L
E
A
S
Q
R
E
L
A
L
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
100
6.6
80
N.A.
80
86.6
N.A.
6.6
73.3
N.A.
13.3
N.A.
0
0
0
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
100
100
N.A.
33.3
80
N.A.
33.3
N.A.
20
40
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
7
0
7
0
20
7
7
14
7
27
7
0
% A
% Cys:
0
7
0
0
0
7
0
0
0
0
14
0
0
40
0
% C
% Asp:
40
14
7
0
40
7
7
0
7
47
0
0
0
0
7
% D
% Glu:
0
40
0
0
0
0
7
0
14
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
20
54
14
0
0
7
0
0
14
27
% F
% Gly:
14
0
14
0
0
7
14
20
7
27
0
7
0
20
0
% G
% His:
20
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% H
% Ile:
0
0
14
0
0
7
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
14
0
0
34
0
0
0
0
7
0
0
0
0
% K
% Leu:
0
7
40
7
7
7
7
0
0
0
34
14
20
7
54
% L
% Met:
0
0
7
54
7
0
0
0
0
0
20
7
14
7
0
% M
% Asn:
20
0
0
0
14
0
0
20
40
7
0
20
0
0
7
% N
% Pro:
0
0
0
7
20
0
0
7
0
0
0
0
0
7
0
% P
% Gln:
0
14
0
0
0
7
0
0
20
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
7
7
0
0
14
7
0
0
34
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
7
20
0
0
7
0
0
0
0
0
27
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _