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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
3.33
Human Site:
S449
Identified Species:
5.24
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
S449
I
H
Y
M
S
P
R
S
F
L
R
L
R
R
P
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
P449
I
H
Y
M
S
P
R
P
F
L
R
L
R
R
P
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
K420
Q
R
W
H
W
Q
K
K
V
I
Y
K
G
L
L
Dog
Lupus familis
XP_537216
492
56859
L456
A
I
G
S
T
Y
L
L
M
C
A
M
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
H444
G
T
Y
L
L
V
H
H
L
S
L
R
P
L
E
Rat
Rattus norvegicus
O88867
478
54335
L441
A
I
G
S
A
Y
I
L
V
H
H
L
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
K420
M
R
W
R
W
Q
N
K
V
V
K
K
G
L
M
Chicken
Gallus gallus
XP_421897
486
55752
I451
L
G
G
T
Y
L
L
I
K
K
L
T
R
G
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
L434
N
K
V
I
T
R
G
L
W
L
C
G
F
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
Q429
F
S
S
M
P
Y
R
Q
C
I
A
N
R
K
W
Honey Bee
Apis mellifera
XP_624246
454
52385
W419
D
C
I
A
N
K
Q
W
Q
D
K
V
L
R
R
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
S420
T
F
S
R
I
P
Y
S
E
V
I
E
R
R
K
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
L431
D
K
I
V
N
N
G
L
I
L
L
G
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
S415
Y
T
M
I
S
F
R
S
D
I
S
Y
S
R
A
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
G472
G
L
P
M
L
A
G
G
L
F
L
W
F
R
Y
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
93.3
0
0
N.A.
6.6
6.6
N.A.
0
6.6
N.A.
6.6
N.A.
20
6.6
26.6
6.6
P-Site Similarity:
100
93.3
20
13.3
N.A.
13.3
13.3
N.A.
26.6
13.3
N.A.
26.6
N.A.
33.3
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
7
7
7
0
0
0
0
14
0
0
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
7
7
7
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% E
% Phe:
7
7
0
0
0
7
0
0
14
7
0
0
14
0
0
% F
% Gly:
14
7
20
0
0
0
20
7
0
0
0
14
14
7
0
% G
% His:
0
14
0
7
0
0
7
7
0
7
7
0
0
0
0
% H
% Ile:
14
14
14
14
7
0
7
7
7
20
7
0
0
0
0
% I
% Lys:
0
14
0
0
0
7
7
14
7
7
14
14
0
7
7
% K
% Leu:
7
7
0
7
14
7
14
27
14
27
27
20
14
27
7
% L
% Met:
7
0
7
27
0
0
0
0
7
0
0
7
0
0
7
% M
% Asn:
7
0
0
0
14
7
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
7
0
7
20
0
7
0
0
0
0
7
7
14
% P
% Gln:
7
0
0
0
0
14
7
7
7
0
0
0
0
0
0
% Q
% Arg:
0
14
0
14
0
7
27
0
0
0
14
7
34
40
20
% R
% Ser:
0
7
14
14
20
0
0
20
0
7
7
0
20
7
14
% S
% Thr:
7
14
0
7
14
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
7
7
0
7
0
0
20
14
0
7
0
7
0
% V
% Trp:
0
0
14
0
14
0
0
7
7
0
0
7
0
0
14
% W
% Tyr:
7
0
20
0
7
20
7
0
0
0
7
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _