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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
34.24
Human Site:
S89
Identified Species:
53.81
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
S89
M
R
A
R
M
I
H
S
L
S
G
K
K
S
A
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
S89
M
R
A
R
M
I
H
S
L
S
G
K
K
S
A
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
S89
M
R
A
R
M
I
H
S
L
S
G
K
K
S
A
Dog
Lupus familis
XP_537216
492
56859
S104
M
R
A
R
M
I
H
S
L
S
G
K
K
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
S89
M
K
A
R
M
I
H
S
L
S
G
K
K
S
A
Rat
Rattus norvegicus
O88867
478
54335
S89
M
K
A
R
M
I
H
S
L
S
G
K
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
S89
M
R
S
R
M
I
H
S
L
S
G
K
K
S
A
Chicken
Gallus gallus
XP_421897
486
55752
T89
M
H
A
R
R
I
H
T
P
L
G
K
K
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
N97
M
H
A
R
M
I
H
N
V
N
G
K
R
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
V110
R
G
R
M
L
H
D
V
R
G
N
S
S
V
V
Honey Bee
Apis mellifera
XP_624246
454
52385
K89
R
G
R
M
I
H
N
K
N
G
S
L
K
E
I
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
K83
Y
A
R
L
I
H
N
K
D
G
K
T
Y
S
R
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
S89
M
H
A
R
L
I
H
S
L
D
G
K
K
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
D87
M
K
G
R
M
I
H
D
L
K
G
R
Q
E
S
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
G97
I
H
G
K
R
P
D
G
K
L
Y
E
E
A
Q
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
53.3
N.A.
60
N.A.
0
6.6
6.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
66.6
N.A.
86.6
N.A.
6.6
20
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
60
0
0
0
0
0
0
0
0
0
0
7
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
14
7
7
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
7
7
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
14
0
0
0
0
7
0
20
74
0
0
0
0
% G
% His:
0
27
0
0
0
20
74
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
14
74
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
20
0
7
0
0
0
14
7
7
7
67
67
0
0
% K
% Leu:
0
0
0
7
14
0
0
0
60
14
0
7
0
0
0
% L
% Met:
74
0
0
14
60
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
14
7
7
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% Q
% Arg:
14
34
20
74
14
0
0
0
7
0
0
7
7
0
7
% R
% Ser:
0
0
7
0
0
0
0
54
0
47
7
7
7
67
14
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
7
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _