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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
38.79
Human Site:
S95
Identified Species:
60.95
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
S95
H
S
L
S
G
K
K
S
A
I
P
Y
G
T
K
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
S95
H
S
L
S
G
K
K
S
A
I
P
Y
G
T
N
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
S95
H
S
L
S
G
K
K
S
A
V
P
Y
G
T
K
Dog
Lupus familis
XP_537216
492
56859
S110
H
S
L
S
G
K
K
S
A
I
P
Y
G
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
S95
H
S
L
S
G
K
K
S
A
I
P
Y
G
N
K
Rat
Rattus norvegicus
O88867
478
54335
S95
H
S
L
S
G
K
K
S
A
I
P
Y
G
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
S95
H
S
L
S
G
K
K
S
A
I
P
Y
G
K
K
Chicken
Gallus gallus
XP_421897
486
55752
Y95
H
T
P
L
G
K
K
Y
S
I
P
Y
G
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
S103
H
N
V
N
G
K
R
S
P
I
P
Y
G
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
V116
D
V
R
G
N
S
S
V
V
L
Y
D
P
I
N
Honey Bee
Apis mellifera
XP_624246
454
52385
E95
N
K
N
G
S
L
K
E
I
L
Y
D
G
V
N
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
S89
N
K
D
G
K
T
Y
S
R
Q
P
Y
G
K
P
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
S95
H
S
L
D
G
K
K
S
A
Q
P
Y
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
E93
H
D
L
K
G
R
Q
E
S
Q
L
Y
G
L
H
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
A103
D
G
K
L
Y
E
E
A
Q
D
Y
D
I
H
G
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
93.3
93.3
100
N.A.
93.3
93.3
N.A.
93.3
60
N.A.
60
N.A.
0
13.3
26.6
86.6
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
93.3
73.3
N.A.
86.6
N.A.
6.6
26.6
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
54
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
7
7
0
0
0
0
0
7
0
20
0
0
0
% D
% Glu:
0
0
0
0
0
7
7
14
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
20
74
0
0
0
0
0
0
0
87
0
7
% G
% His:
74
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% H
% Ile:
0
0
0
0
0
0
0
0
7
54
0
0
7
7
0
% I
% Lys:
0
14
7
7
7
67
67
0
0
0
0
0
0
27
60
% K
% Leu:
0
0
60
14
0
7
0
0
0
14
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
14
7
7
7
7
0
0
0
0
0
0
0
0
14
20
% N
% Pro:
0
0
7
0
0
0
0
0
7
0
74
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
7
0
7
20
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
7
7
0
7
0
0
0
0
0
0
% R
% Ser:
0
54
0
47
7
7
7
67
14
0
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
7
0
0
0
0
0
0
0
34
0
% T
% Val:
0
7
7
0
0
0
0
7
7
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
7
0
0
20
80
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _