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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
23.94
Human Site:
T399
Identified Species:
37.62
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
T399
S
T
F
I
P
L
Y
T
M
V
T
F
S
R
I
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
T399
S
T
F
I
P
L
Y
T
M
V
T
F
S
R
I
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
F376
A
H
V
N
S
S
W
F
I
F
Q
K
N
M
G
Dog
Lupus familis
XP_537216
492
56859
T414
S
T
F
I
P
L
Y
T
M
I
T
F
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
T399
S
T
F
I
P
L
Y
T
M
V
A
F
T
R
I
Rat
Rattus norvegicus
O88867
478
54335
T399
S
T
F
I
P
L
Y
T
M
V
A
F
T
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
F376
S
H
V
N
S
R
W
F
L
F
R
T
Y
L
D
Chicken
Gallus gallus
XP_421897
486
55752
T409
S
T
I
I
P
L
Y
T
M
V
T
F
S
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
N392
I
F
R
K
Y
L
D
N
L
L
H
F
F
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
V385
D
L
A
M
Y
N
Y
V
E
M
R
D
L
T
K
Honey Bee
Apis mellifera
XP_624246
454
52385
S377
R
D
L
V
R
K
K
S
F
L
V
R
K
Y
I
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
E377
L
A
M
Y
N
Y
E
E
L
K
D
L
V
N
K
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
W389
L
F
R
K
K
V
D
W
L
L
N
W
F
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
A370
L
V
S
I
T
E
L
A
K
R
N
Y
K
E
M
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
T430
V
P
S
L
G
W
Q
T
K
Y
S
R
V
S
F
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
6.6
93.3
N.A.
13.3
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
26.6
100
N.A.
93.3
93.3
N.A.
20
93.3
N.A.
26.6
N.A.
20
26.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
0
7
0
0
14
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
14
0
0
0
7
7
0
0
7
% D
% Glu:
0
0
0
0
0
7
7
7
7
0
0
0
0
7
0
% E
% Phe:
0
14
34
0
0
0
0
14
7
14
0
47
14
0
7
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
14
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
7
47
0
0
0
0
7
7
0
0
0
0
47
% I
% Lys:
0
0
0
14
7
7
7
0
14
7
0
7
14
0
14
% K
% Leu:
20
7
7
7
0
47
7
0
27
20
0
7
7
14
0
% L
% Met:
0
0
7
7
0
0
0
0
40
7
0
0
0
14
7
% M
% Asn:
0
0
0
14
7
7
0
7
0
0
14
0
7
7
0
% N
% Pro:
0
7
0
0
40
0
0
0
0
0
0
0
0
0
14
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% Q
% Arg:
7
0
14
0
7
7
0
0
0
7
14
14
0
40
0
% R
% Ser:
47
0
14
0
14
7
0
7
0
0
7
0
27
7
0
% S
% Thr:
0
40
0
0
7
0
0
47
0
0
27
7
14
7
0
% T
% Val:
7
7
14
7
0
7
0
7
0
34
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
7
14
7
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
14
7
47
0
0
7
0
7
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _