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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
8.48
Human Site:
T47
Identified Species:
13.33
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
T47
R
E
D
T
R
V
A
T
F
T
R
G
R
S
I
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
T47
R
E
D
S
R
V
A
T
F
T
R
G
R
S
I
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
D47
R
E
D
P
R
V
A
D
F
T
R
G
R
S
I
Dog
Lupus familis
XP_537216
492
56859
K62
R
E
D
I
R
V
A
K
F
A
R
G
R
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
K47
R
E
D
I
R
V
A
K
S
A
R
G
R
S
I
Rat
Rattus norvegicus
O88867
478
54335
N47
R
E
D
I
R
V
A
N
F
M
R
G
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
K47
R
E
D
L
R
V
A
K
V
A
R
G
R
S
I
Chicken
Gallus gallus
XP_421897
486
55752
S47
R
E
D
M
R
V
S
S
F
A
R
G
R
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
K55
R
E
D
I
R
Q
A
K
V
V
K
G
R
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
L67
R
E
D
I
R
Q
A
L
V
V
Q
G
R
S
I
Honey Bee
Apis mellifera
XP_624246
454
52385
V45
Y
R
P
D
I
R
T
V
D
C
W
G
Q
S
I
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
G44
R
T
M
K
H
V
Q
G
R
S
I
N
L
A
L
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
E47
R
E
D
I
R
R
A
E
H
V
A
G
R
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
K45
R
L
D
T
T
K
N
K
N
L
K
S
I
N
L
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
P47
L
R
D
P
S
T
T
P
L
N
F
T
R
S
I
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
93.3
86.6
80
N.A.
73.3
80
N.A.
73.3
73.3
N.A.
60
N.A.
60
20
13.3
60
P-Site Similarity:
100
100
86.6
80
N.A.
73.3
80
N.A.
73.3
86.6
N.A.
66.6
N.A.
66.6
26.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
0
27
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
87
7
0
0
0
7
7
0
0
0
0
0
0
% D
% Glu:
0
74
0
0
0
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
80
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
40
7
0
0
0
0
0
7
0
7
0
87
% I
% Lys:
0
0
0
7
0
7
0
34
0
0
14
0
0
0
0
% K
% Leu:
7
7
0
7
0
0
0
7
7
7
0
0
7
0
14
% L
% Met:
0
0
7
7
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
7
7
0
7
0
7
0
% N
% Pro:
0
0
7
14
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
14
7
0
0
0
7
0
7
0
0
% Q
% Arg:
87
14
0
0
74
14
0
0
7
0
54
0
80
0
0
% R
% Ser:
0
0
0
7
7
0
7
7
7
7
0
7
0
87
0
% S
% Thr:
0
7
0
14
7
7
14
14
0
20
0
7
0
0
0
% T
% Val:
0
0
0
0
0
60
0
7
20
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _