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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
35.15
Human Site:
Y125
Identified Species:
55.24
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
Y125
L
L
T
A
A
E
K
Y
P
N
V
K
M
H
F
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
Y125
L
L
T
A
A
E
K
Y
P
N
V
K
M
H
F
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
N125
L
L
T
A
A
E
K
N
P
G
V
K
M
H
F
Dog
Lupus familis
XP_537216
492
56859
Y140
L
L
T
A
V
E
K
Y
P
N
V
K
V
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
Y125
L
L
T
A
V
E
S
Y
A
N
A
K
V
H
F
Rat
Rattus norvegicus
O88867
478
54335
Y125
L
L
T
A
V
E
S
Y
P
N
A
K
V
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
Y125
L
L
T
E
V
E
K
Y
P
N
A
K
V
H
F
Chicken
Gallus gallus
XP_421897
486
55752
Y125
L
L
T
A
A
E
K
Y
S
N
T
K
L
Y
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
Y133
L
L
T
A
A
E
A
Y
P
N
T
R
L
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
L146
L
L
N
A
C
D
K
L
P
N
I
R
C
H
F
Honey Bee
Apis mellifera
XP_624246
454
52385
Y125
L
L
N
A
A
E
K
Y
S
E
V
S
L
H
F
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
S119
M
I
T
Q
A
E
K
S
P
N
V
K
F
F
F
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
V125
L
L
S
A
A
E
K
V
E
S
V
T
M
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
S123
L
L
D
E
L
E
K
S
T
T
E
L
K
F
G
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
F133
E
M
P
N
V
T
F
F
F
N
H
K
L
T
G
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
100
86.6
86.6
N.A.
66.6
73.3
N.A.
73.3
73.3
N.A.
66.6
N.A.
53.3
66.6
60
66.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
73.3
80
N.A.
80
86.6
N.A.
86.6
N.A.
73.3
73.3
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
74
54
0
7
0
7
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
14
0
87
0
0
7
7
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
7
7
0
0
0
7
14
87
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
67
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
74
0
0
0
0
67
7
0
0
% K
% Leu:
87
87
0
0
7
0
0
7
0
0
0
7
27
0
0
% L
% Met:
7
7
0
0
0
0
0
0
0
0
0
0
27
0
0
% M
% Asn:
0
0
14
7
0
0
0
7
0
74
0
0
0
7
0
% N
% Pro:
0
0
7
0
0
0
0
0
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% R
% Ser:
0
0
7
0
0
0
14
14
14
7
0
7
0
0
0
% S
% Thr:
0
0
67
0
0
7
0
0
7
7
14
7
0
7
0
% T
% Val:
0
0
0
0
34
0
0
7
0
0
47
0
27
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _