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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KMO
All Species:
22.12
Human Site:
Y206
Identified Species:
34.76
UniProt:
O15229
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15229
NP_003670.2
486
55810
Y206
I
P
P
K
N
G
D
Y
A
M
E
P
N
Y
L
Chimpanzee
Pan troglodytes
XP_001160394
490
56253
Y206
I
P
P
K
N
G
D
Y
A
M
E
P
N
Y
L
Rhesus Macaque
Macaca mulatta
XP_001093900
458
52405
Y206
I
P
P
K
N
G
D
Y
A
M
E
P
N
Y
L
Dog
Lupus familis
XP_537216
492
56859
Y221
I
P
P
K
N
G
D
Y
A
M
E
P
N
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WN4
479
54513
Y206
I
P
P
K
N
G
E
Y
A
M
E
P
N
C
L
Rat
Rattus norvegicus
O88867
478
54335
Y206
I
P
P
K
N
G
E
Y
A
M
E
P
N
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514157
469
53167
F206
I
P
P
K
N
G
E
F
A
M
E
P
N
S
L
Chicken
Gallus gallus
XP_421897
486
55752
F216
I
P
P
R
D
G
D
F
A
M
E
P
N
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1RLY6
474
54228
F214
M
P
P
K
D
G
D
F
A
M
E
P
N
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z746
465
52863
F227
I
P
S
K
S
G
D
F
Q
M
P
A
N
Y
L
Honey Bee
Apis mellifera
XP_624246
454
52385
F208
P
S
G
K
N
N
E
F
M
M
S
N
K
H
L
Nematode Worm
Caenorhab. elegans
Q21795
461
52293
F216
I
M
A
N
N
N
E
F
A
F
E
E
N
V
F
Sea Urchin
Strong. purpuratus
XP_796984
469
53490
D206
V
P
P
V
P
G
T
D
G
Q
H
N
M
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38169
460
52411
K207
I
P
P
T
E
E
F
K
P
N
Y
G
G
N
F
Red Bread Mold
Neurospora crassa
Q7S3C9
507
57299
F221
S
S
S
A
K
S
K
F
R
I
S
P
N
H
L
Conservation
Percent
Protein Identity:
100
97.7
89.5
80.8
N.A.
78.5
77.1
N.A.
69.9
68.5
N.A.
60
N.A.
43.2
44.4
42.7
50.2
Protein Similarity:
100
98.3
91.5
88.2
N.A.
87.8
87
N.A.
82.5
81.8
N.A.
77.5
N.A.
60.2
61.9
63.7
69.3
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
80
N.A.
80
N.A.
60
26.6
33.3
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
100
N.A.
100
N.A.
73.3
46.6
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
37
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
52.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
0
0
67
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% C
% Asp:
0
0
0
0
14
0
47
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
7
34
0
0
0
67
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
47
0
7
0
0
0
0
14
% F
% Gly:
0
0
7
0
0
74
0
0
7
0
0
7
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
0
% H
% Ile:
74
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% I
% Lys:
0
0
0
67
7
0
7
7
0
0
0
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% L
% Met:
7
7
0
0
0
0
0
0
7
74
0
0
7
0
0
% M
% Asn:
0
0
0
7
60
14
0
0
0
7
0
14
80
7
0
% N
% Pro:
7
80
74
0
7
0
0
0
7
0
7
67
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
7
14
14
0
7
7
0
0
0
0
14
0
0
7
0
% S
% Thr:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
7
0
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _