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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF185
All Species:
12.42
Human Site:
S374
Identified Species:
34.17
UniProt:
O15231
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15231
NP_001171585
457
49187
S374
N
V
S
S
I
E
D
S
F
A
M
E
K
K
P
Chimpanzee
Pan troglodytes
XP_521357
777
83238
S696
N
V
S
S
I
E
D
S
F
A
M
E
K
K
P
Rhesus Macaque
Macaca mulatta
XP_001082585
626
67128
S543
S
V
S
S
I
E
D
S
F
T
M
E
K
K
P
Dog
Lupus familis
XP_549348
734
79595
S651
S
V
R
S
I
E
D
S
C
D
M
E
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q62394
352
38304
L271
P
S
S
I
E
D
S
L
D
L
A
K
K
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514947
991
108945
E789
L
D
D
W
S
D
I
E
R
S
T
S
S
A
S
Chicken
Gallus gallus
XP_420277
173
19428
G92
D
L
T
D
L
E
R
G
T
Y
S
H
H
S
Y
Frog
Xenopus laevis
NP_001085823
664
74335
N574
L
N
R
S
Y
E
N
N
I
A
A
N
S
I
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21184
299
29289
P218
E
P
I
T
P
G
A
P
G
P
Q
G
T
P
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.3
65.9
44.6
N.A.
54.4
N.A.
N.A.
23
23.6
20.6
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
100
53.4
68.8
50.6
N.A.
63.6
N.A.
N.A.
31.2
30.8
37.2
N.A.
N.A.
N.A.
N.A.
29.3
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
20
N.A.
N.A.
0
6.6
20
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
33.3
N.A.
N.A.
13.3
33.3
33.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
34
23
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
12
12
12
0
23
45
0
12
12
0
0
0
0
0
% D
% Glu:
12
0
0
0
12
67
0
12
0
0
0
45
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
12
12
0
0
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% H
% Ile:
0
0
12
12
45
0
12
0
12
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
12
56
45
12
% K
% Leu:
23
12
0
0
12
0
0
12
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% M
% Asn:
23
12
0
0
0
0
12
12
0
0
0
12
0
0
0
% N
% Pro:
12
12
0
0
12
0
0
12
0
12
0
0
0
23
56
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
23
0
0
0
12
0
12
0
0
0
0
0
0
% R
% Ser:
23
12
45
56
12
0
12
45
0
12
12
12
23
12
12
% S
% Thr:
0
0
12
12
0
0
0
0
12
12
12
0
12
0
0
% T
% Val:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _