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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPS12
All Species:
18.18
Human Site:
T124
Identified Species:
30.77
UniProt:
O15235
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15235
NP_066930.1
138
15173
T124
D
L
P
G
V
K
L
T
V
V
R
G
K
Y
D
Chimpanzee
Pan troglodytes
XP_524259
138
15173
T124
D
L
P
G
V
K
L
T
V
V
R
G
K
Y
D
Rhesus Macaque
Macaca mulatta
XP_001086153
139
15250
T124
D
L
P
G
V
K
L
T
V
V
R
G
K
Y
D
Dog
Lupus familis
XP_541631
167
18371
T124
D
L
P
G
V
K
L
T
V
V
R
G
K
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
O35680
139
15419
K124
D
L
P
G
V
K
L
K
V
V
R
G
K
Y
D
Rat
Rattus norvegicus
NP_001099709
139
15423
K124
D
L
P
G
V
K
L
K
V
V
R
G
K
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519076
117
13082
R104
G
V
R
L
T
V
V
R
G
K
Y
D
C
G
H
Chicken
Gallus gallus
XP_001233807
135
14682
T120
D
L
P
G
V
K
L
T
V
V
R
G
K
Y
D
Frog
Xenopus laevis
NP_001080645
150
16554
K135
D
L
P
G
V
K
L
K
I
V
R
G
K
Y
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10735
140
15514
K124
D
V
P
G
V
K
L
K
A
V
R
G
V
Y
D
Honey Bee
Apis mellifera
XP_393221
171
19065
R155
D
T
P
G
V
K
I
R
C
V
R
G
K
Y
D
Nematode Worm
Caenorhab. elegans
NP_508023
157
17352
N142
D
L
I
S
V
K
A
N
I
V
R
G
K
Y
D
Sea Urchin
Strong. purpuratus
XP_795803
130
14610
I117
P
G
V
K
H
T
V
I
R
G
K
Y
D
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53732
153
16898
H124
D
L
P
G
V
K
Y
H
V
I
R
G
A
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
94.9
67
N.A.
84.8
86.3
N.A.
71
70.2
64.6
N.A.
N.A.
55
43.8
45.8
61.5
Protein Similarity:
100
99.2
95.6
71.2
N.A.
89.9
90.6
N.A.
74.6
74.6
73.3
N.A.
N.A.
62.8
56.1
52.8
71.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
100
86.6
N.A.
N.A.
73.3
73.3
66.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
100
93.3
N.A.
N.A.
80
80
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% C
% Asp:
86
0
0
0
0
0
0
0
0
0
0
8
8
0
86
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
79
0
0
0
0
8
8
0
86
0
15
8
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
8
8
15
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
86
0
29
0
8
8
0
72
0
0
% K
% Leu:
0
72
0
8
0
0
65
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
79
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
15
8
0
86
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
8
8
0
36
0
0
0
0
0
0
0
% T
% Val:
0
15
8
0
86
8
15
0
58
79
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
8
0
79
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _