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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPS12 All Species: 28.79
Human Site: T52 Identified Species: 48.72
UniProt: O15235 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15235 NP_066930.1 138 15173 T52 P P R K L G P T E G R P Q L K
Chimpanzee Pan troglodytes XP_524259 138 15173 T52 P P R K L G P T E G R P Q L K
Rhesus Macaque Macaca mulatta XP_001086153 139 15250 T52 P P R K L G P T E G R P Q L K
Dog Lupus familis XP_541631 167 18371 T52 P P P P L G P T A G R P Q L K
Cat Felis silvestris
Mouse Mus musculus O35680 139 15419 T52 P P K R L G P T E G R P Q L K
Rat Rattus norvegicus NP_001099709 139 15423 T52 P P K R L G P T E G R P Q L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519076 117 13082 R32 K L G P T E G R P Q L K G V V
Chicken Gallus gallus XP_001233807 135 14682 T48 P P P K P G P T F G R P Q L K
Frog Xenopus laevis NP_001080645 150 16554 T63 D P P Q L G P T F G C P Q L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10735 140 15514 L52 T R P P R Q P L D G K P F A K
Honey Bee Apis mellifera XP_393221 171 19065 L83 Q K K K K N P L S G K P F A K
Nematode Worm Caenorhab. elegans NP_508023 157 17352 I70 R S K D K S A I S G Y S H Y K
Sea Urchin Strong. purpuratus XP_795803 130 14610 K45 N M T F A M D K R P Q M K G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53732 153 16898 L52 K I S T A P Q L D Q C P Q R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 94.9 67 N.A. 84.8 86.3 N.A. 71 70.2 64.6 N.A. N.A. 55 43.8 45.8 61.5
Protein Similarity: 100 99.2 95.6 71.2 N.A. 89.9 90.6 N.A. 74.6 74.6 73.3 N.A. N.A. 62.8 56.1 52.8 71.7
P-Site Identity: 100 100 100 80 N.A. 86.6 86.6 N.A. 0 80 66.6 N.A. N.A. 26.6 33.3 13.3 0
P-Site Similarity: 100 100 100 80 N.A. 100 100 N.A. 6.6 80 73.3 N.A. N.A. 40 46.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 8 0 8 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 8 0 15 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 36 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 15 0 0 0 15 0 0 % F
% Gly: 0 0 8 0 0 58 8 0 0 79 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 15 8 29 36 15 0 0 8 0 0 15 8 8 0 86 % K
% Leu: 0 8 0 0 50 0 0 22 0 0 8 0 0 58 0 % L
% Met: 0 8 0 0 0 8 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 58 29 22 8 8 72 0 8 8 0 79 0 0 0 % P
% Gln: 8 0 0 8 0 8 8 0 0 15 8 0 65 0 0 % Q
% Arg: 8 8 22 15 8 0 0 8 8 0 50 0 0 8 0 % R
% Ser: 0 8 8 0 0 8 0 0 15 0 0 8 0 0 0 % S
% Thr: 8 0 8 8 8 0 0 58 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _