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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LEPROT
All Species:
10.61
Human Site:
Y57
Identified Species:
23.33
UniProt:
O15243
Number Species:
10
Phosphosite Substitution
Charge Score:
0.6
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15243
NP_059996.1
131
14254
Y57
F
I
A
K
R
V
T
Y
D
S
D
A
T
S
S
Chimpanzee
Pan troglodytes
XP_528101
194
20282
D120
C
I
A
R
R
L
V
D
D
T
D
A
M
S
N
Rhesus Macaque
Macaca mulatta
XP_001091320
124
13818
C59
S
D
A
T
S
S
A
C
R
E
L
A
Y
F
F
Dog
Lupus familis
XP_865019
110
12161
T54
E
L
A
Y
F
F
T
T
G
I
V
V
S
A
F
Cat
Felis silvestris
Mouse
Mus musculus
O89013
131
14297
Y57
F
I
A
K
R
V
T
Y
D
S
D
A
T
S
S
Rat
Rattus norvegicus
Q9JLS8
131
14301
Y57
F
I
A
K
R
V
T
Y
D
S
D
A
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515248
260
28693
D186
F
I
A
T
R
A
S
D
D
S
D
S
G
S
N
Chicken
Gallus gallus
NP_001007959
131
14370
D57
F
I
A
R
R
V
S
D
D
S
D
A
A
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002390
131
14174
E57
C
I
S
R
R
V
V
E
D
S
D
S
A
S
N
Tiger Blowfish
Takifugu rubipres
NP_001129622
131
14244
D57
C
I
S
R
R
V
V
D
D
T
D
S
A
S
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18319
132
14098
E57
L
I
A
R
R
F
Q
E
D
M
T
G
T
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.8
79.3
81.6
N.A.
94.6
96.9
N.A.
45.3
87.7
N.A.
68.6
67.9
N.A.
N.A.
46.9
N.A.
Protein Similarity:
100
54.6
81.6
83.2
N.A.
97.7
99.2
N.A.
47.6
93.1
N.A.
80.1
80.1
N.A.
N.A.
65.1
N.A.
P-Site Identity:
100
46.6
13.3
13.3
N.A.
100
100
N.A.
53.3
73.3
N.A.
46.6
40
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
73.3
13.3
33.3
N.A.
100
100
N.A.
73.3
86.6
N.A.
73.3
73.3
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
82
0
0
10
10
0
0
0
0
55
28
10
10
% A
% Cys:
28
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
37
82
0
73
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% E
% Phe:
46
0
0
0
10
19
0
0
0
0
0
0
0
10
19
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
82
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
37
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
46
82
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
19
0
10
10
19
0
0
55
0
28
10
73
37
% S
% Thr:
0
0
0
19
0
0
37
10
0
19
10
0
37
0
0
% T
% Val:
0
0
0
0
0
55
28
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
28
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _