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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX3
All Species:
22.42
Human Site:
S405
Identified Species:
37.95
UniProt:
O15254
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15254
NP_001095137.1
700
77629
S405
R
E
I
H
A
L
A
S
A
S
K
P
L
A
S
Chimpanzee
Pan troglodytes
XP_001138526
700
77720
S405
R
E
I
H
A
L
A
S
A
S
K
P
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001118756
503
55946
E221
Q
F
G
P
T
Q
E
E
E
I
A
V
L
E
Y
Dog
Lupus familis
XP_545908
700
78858
S405
R
E
I
H
A
L
V
S
A
S
K
P
L
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL9
700
78385
S405
R
E
I
H
A
L
A
S
A
G
K
P
L
A
S
Rat
Rattus norvegicus
Q63448
700
78427
S405
R
E
I
H
A
L
A
S
A
G
K
P
L
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420814
706
79939
A412
R
E
I
H
A
L
S
A
A
S
K
P
L
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998312
692
78016
C397
R
E
I
H
A
L
S
C
A
S
K
P
L
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
D378
E
I
E
Q
G
N
L
D
R
L
P
E
M
H
A
Honey Bee
Apis mellifera
XP_395486
676
76982
L388
E
G
M
E
I
H
A
L
S
S
A
T
K
P
V
Nematode Worm
Caenorhab. elegans
P34355
659
74696
H373
N
C
I
K
Q
L
S
H
G
N
S
D
V
L
A
Sea Urchin
Strong. purpuratus
XP_786025
740
82973
S446
K
E
M
H
A
L
S
S
A
S
K
P
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65201
692
77462
Y398
M
L
A
S
T
Y
A
Y
H
F
A
T
V
Y
L
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
N436
T
V
S
K
K
L
K
N
L
F
I
D
S
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
67.1
76.7
N.A.
73.4
74.2
N.A.
N.A.
64.5
N.A.
64.7
N.A.
28.2
42.2
30
51.6
Protein Similarity:
100
99.1
69.1
87.2
N.A.
84.7
84
N.A.
N.A.
80.5
N.A.
80.1
N.A.
47.2
61
48.1
68.2
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
80
N.A.
0
13.3
13.3
73.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
86.6
N.A.
13.3
26.6
40
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
58
0
43
8
58
0
22
0
0
43
15
% A
% Cys:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
15
0
0
0
% D
% Glu:
15
58
8
8
0
0
8
8
8
0
0
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
0
8
8
0
8
0
0
0
8
15
0
0
0
8
0
% G
% His:
0
0
0
58
0
8
0
8
8
0
0
0
0
8
0
% H
% Ile:
0
8
58
0
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
8
0
0
15
8
0
8
0
0
0
58
0
8
0
0
% K
% Leu:
0
8
0
0
0
72
8
8
8
8
0
0
65
8
8
% L
% Met:
8
0
15
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
8
58
0
8
0
% P
% Gln:
8
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
0
29
43
8
50
8
0
8
15
65
% S
% Thr:
8
0
0
0
15
0
0
0
0
0
0
15
0
0
0
% T
% Val:
0
8
0
0
0
0
8
0
0
0
0
8
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _