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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX3
All Species:
8.79
Human Site:
S579
Identified Species:
14.87
UniProt:
O15254
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15254
NP_001095137.1
700
77629
S579
H
E
H
V
H
Q
P
S
V
P
P
S
L
R
A
Chimpanzee
Pan troglodytes
XP_001138526
700
77720
C579
H
E
H
V
H
Q
P
C
V
P
P
S
L
R
A
Rhesus Macaque
Macaca mulatta
XP_001118756
503
55946
S390
S
I
A
D
C
L
D
S
A
V
A
L
A
A
Y
Dog
Lupus familis
XP_545908
700
78858
S579
H
E
Y
T
H
Q
P
S
V
P
P
P
L
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL9
700
78385
G579
H
E
H
I
H
S
S
G
L
S
P
S
L
R
T
Rat
Rattus norvegicus
Q63448
700
78427
S579
H
E
H
T
H
S
S
S
V
P
P
S
L
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420814
706
79939
N585
H
D
Y
T
H
D
P
N
V
P
S
T
L
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998312
692
78016
Q571
H
D
L
I
Q
D
E
Q
T
P
A
V
L
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
R552
T
E
L
L
A
L
S
R
E
V
S
P
E
L
A
Honey Bee
Apis mellifera
XP_395486
676
76982
L563
I
E
C
I
Q
N
P
L
W
R
S
E
E
R
N
Nematode Worm
Caenorhab. elegans
P34355
659
74696
S546
V
K
S
V
Q
E
V
S
D
E
A
V
H
D
V
Sea Urchin
Strong. purpuratus
XP_786025
740
82973
D619
W
N
Y
L
Q
T
G
D
F
I
P
E
Q
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65201
692
77462
G567
K
H
S
K
T
L
G
G
F
G
A
W
N
R
C
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
K615
H
I
S
D
E
I
T
K
E
S
M
W
N
V
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
67.1
76.7
N.A.
73.4
74.2
N.A.
N.A.
64.5
N.A.
64.7
N.A.
28.2
42.2
30
51.6
Protein Similarity:
100
99.1
69.1
87.2
N.A.
84.7
84
N.A.
N.A.
80.5
N.A.
80.1
N.A.
47.2
61
48.1
68.2
P-Site Identity:
100
93.3
6.6
80
N.A.
53.3
73.3
N.A.
N.A.
40
N.A.
26.6
N.A.
13.3
20
13.3
13.3
P-Site Similarity:
100
93.3
6.6
86.6
N.A.
66.6
73.3
N.A.
N.A.
73.3
N.A.
46.6
N.A.
20
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
0
8
0
29
0
8
8
36
% A
% Cys:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
15
0
15
0
15
8
8
8
0
0
0
0
8
0
% D
% Glu:
0
50
0
0
8
8
8
0
15
8
0
15
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
15
15
0
8
0
0
0
0
0
% G
% His:
58
8
29
0
43
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
15
0
22
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
15
0
22
0
8
8
0
0
8
50
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
8
0
0
0
0
15
0
8
% N
% Pro:
0
0
0
0
0
0
36
0
0
43
43
15
0
0
8
% P
% Gln:
0
0
0
0
29
22
0
8
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
58
0
% R
% Ser:
8
0
22
0
0
15
22
36
0
15
22
29
0
0
8
% S
% Thr:
8
0
0
22
8
8
8
0
8
0
0
8
0
8
15
% T
% Val:
8
0
0
22
0
0
8
0
36
15
0
15
0
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% W
% Tyr:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _