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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX3
All Species:
28.48
Human Site:
S614
Identified Species:
48.21
UniProt:
O15254
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15254
NP_001095137.1
700
77629
S614
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
E
V
Chimpanzee
Pan troglodytes
XP_001138526
700
77720
S614
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
E
V
Rhesus Macaque
Macaca mulatta
XP_001118756
503
55946
A425
S
G
S
S
D
F
E
A
R
N
N
C
Q
V
S
Dog
Lupus familis
XP_545908
700
78858
S614
L
Y
Q
G
G
Y
F
S
G
E
E
A
G
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL9
700
78385
S614
L
Y
R
G
G
Y
I
S
G
E
Q
T
G
R
A
Rat
Rattus norvegicus
Q63448
700
78427
S614
L
Y
R
G
G
Y
I
S
G
E
Q
T
G
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420814
706
79939
S620
L
Y
Q
G
G
Y
V
S
G
E
Q
A
G
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998312
692
78016
S606
L
Y
Q
G
G
Y
F
S
G
G
Q
P
V
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
L587
D
F
L
R
F
I
D
L
T
D
Q
D
V
T
K
Honey Bee
Apis mellifera
XP_395486
676
76982
S598
F
Y
A
G
G
Y
A
S
T
K
S
N
M
D
S
Nematode Worm
Caenorhab. elegans
P34355
659
74696
E581
T
A
N
G
Y
L
S
E
S
D
V
Q
Q
I
R
Sea Urchin
Strong. purpuratus
XP_786025
740
82973
S654
L
Y
Q
G
G
Y
F
S
G
A
E
T
A
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65201
692
77462
P602
I
E
A
V
K
N
C
P
D
P
S
A
K
A
A
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
K650
F
T
P
D
Q
I
S
K
V
V
Q
P
Q
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
67.1
76.7
N.A.
73.4
74.2
N.A.
N.A.
64.5
N.A.
64.7
N.A.
28.2
42.2
30
51.6
Protein Similarity:
100
99.1
69.1
87.2
N.A.
84.7
84
N.A.
N.A.
80.5
N.A.
80.1
N.A.
47.2
61
48.1
68.2
P-Site Identity:
100
100
0
73.3
N.A.
73.3
73.3
N.A.
N.A.
73.3
N.A.
60
N.A.
6.6
33.3
6.6
53.3
P-Site Similarity:
100
100
13.3
100
N.A.
73.3
80
N.A.
N.A.
80
N.A.
73.3
N.A.
20
46.6
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
0
8
8
0
8
0
36
8
8
22
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
8
8
0
8
0
8
15
0
8
0
15
0
% D
% Glu:
0
8
0
0
0
0
8
8
0
43
15
0
0
15
0
% E
% Phe:
15
8
0
0
8
8
36
0
0
0
0
0
0
0
15
% F
% Gly:
0
8
0
72
65
0
0
0
58
8
0
0
43
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
15
15
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
8
0
0
8
15
8
% K
% Leu:
58
0
8
0
0
8
0
8
0
0
0
0
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
8
8
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
8
0
15
0
0
0
% P
% Gln:
0
0
29
0
8
0
0
0
0
0
58
8
22
0
0
% Q
% Arg:
0
0
29
8
0
0
0
0
8
0
0
0
0
22
8
% R
% Ser:
8
0
8
8
0
0
15
65
8
0
15
0
0
0
15
% S
% Thr:
8
8
0
0
0
0
0
0
15
0
0
22
0
8
0
% T
% Val:
0
0
0
8
0
0
8
0
8
8
8
0
15
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
65
0
0
8
65
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _