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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX3
All Species:
30
Human Site:
Y612
Identified Species:
50.77
UniProt:
O15254
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15254
NP_001095137.1
700
77629
Y612
A
L
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
Chimpanzee
Pan troglodytes
XP_001138526
700
77720
Y612
A
L
L
Y
R
G
G
Y
F
S
G
E
Q
A
G
Rhesus Macaque
Macaca mulatta
XP_001118756
503
55946
F423
K
R
S
G
S
S
D
F
E
A
R
N
N
C
Q
Dog
Lupus familis
XP_545908
700
78858
Y612
A
L
L
Y
Q
G
G
Y
F
S
G
E
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL9
700
78385
Y612
A
L
L
Y
R
G
G
Y
I
S
G
E
Q
T
G
Rat
Rattus norvegicus
Q63448
700
78427
Y612
A
L
L
Y
R
G
G
Y
I
S
G
E
Q
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420814
706
79939
Y618
A
V
L
Y
Q
G
G
Y
V
S
G
E
Q
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998312
692
78016
Y604
A
I
L
Y
Q
G
G
Y
F
S
G
G
Q
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
I585
I
G
D
F
L
R
F
I
D
L
T
D
Q
D
V
Honey Bee
Apis mellifera
XP_395486
676
76982
Y596
G
D
F
Y
A
G
G
Y
A
S
T
K
S
N
M
Nematode Worm
Caenorhab. elegans
P34355
659
74696
L579
D
L
T
A
N
G
Y
L
S
E
S
D
V
Q
Q
Sea Urchin
Strong. purpuratus
XP_786025
740
82973
Y652
A
T
L
Y
Q
G
G
Y
F
S
G
A
E
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65201
692
77462
N600
K
F
I
E
A
V
K
N
C
P
D
P
S
A
K
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
I648
K
I
F
T
P
D
Q
I
S
K
V
V
Q
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
67.1
76.7
N.A.
73.4
74.2
N.A.
N.A.
64.5
N.A.
64.7
N.A.
28.2
42.2
30
51.6
Protein Similarity:
100
99.1
69.1
87.2
N.A.
84.7
84
N.A.
N.A.
80.5
N.A.
80.1
N.A.
47.2
61
48.1
68.2
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
N.A.
66.6
N.A.
6.6
33.3
13.3
60
P-Site Similarity:
100
100
13.3
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
N.A.
80
N.A.
20
40
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
8
15
0
0
0
8
8
0
8
0
36
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
8
8
8
0
0
8
8
0
8
0
8
15
0
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
8
0
43
15
0
0
% E
% Phe:
0
8
15
8
0
0
8
8
36
0
0
0
0
0
0
% F
% Gly:
8
8
0
8
0
72
65
0
0
0
58
8
0
0
43
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
15
8
0
0
0
0
15
15
0
0
0
0
0
0
% I
% Lys:
22
0
0
0
0
0
8
0
0
8
0
8
0
0
8
% K
% Leu:
0
43
58
0
8
0
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
8
8
8
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
8
0
15
0
% P
% Gln:
0
0
0
0
29
0
8
0
0
0
0
0
58
8
22
% Q
% Arg:
0
8
0
0
29
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
8
8
0
0
15
65
8
0
15
0
0
% S
% Thr:
0
8
8
8
0
0
0
0
0
0
15
0
0
22
0
% T
% Val:
0
8
0
0
0
8
0
0
8
0
8
8
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
65
0
0
8
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _