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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX3
All Species:
15.15
Human Site:
Y74
Identified Species:
25.64
UniProt:
O15254
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15254
NP_001095137.1
700
77629
Y74
A
D
L
S
L
E
K
Y
R
E
L
N
F
L
R
Chimpanzee
Pan troglodytes
XP_001138526
700
77720
Y74
A
D
L
S
L
E
K
Y
R
E
L
N
F
L
R
Rhesus Macaque
Macaca mulatta
XP_001118756
503
55946
Dog
Lupus familis
XP_545908
700
78858
Y74
E
D
I
S
L
D
R
Y
R
E
L
S
F
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPL9
700
78385
L74
A
D
L
P
L
E
K
L
R
E
L
N
F
L
R
Rat
Rattus norvegicus
Q63448
700
78427
E74
A
D
L
P
L
E
K
E
R
E
L
N
F
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420814
706
79939
Y82
E
E
L
S
R
E
K
Y
Q
E
L
T
F
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998312
692
78016
C74
R
E
L
T
F
L
R
C
K
Q
L
F
K
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
I80
A
C
I
I
G
E
K
I
R
K
L
R
A
D
G
Honey Bee
Apis mellifera
XP_395486
676
76982
L75
C
N
S
R
V
R
A
L
K
D
N
D
I
A
N
Nematode Worm
Caenorhab. elegans
P34355
659
74696
R76
E
R
M
E
D
V
S
R
K
L
K
N
L
M
E
Sea Urchin
Strong. purpuratus
XP_786025
740
82973
S115
R
P
L
T
M
E
E
S
R
A
L
V
F
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65201
692
77462
R100
E
I
S
K
D
D
H
R
E
L
C
M
N
Q
L
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
H100
D
I
K
T
V
R
K
H
F
R
D
T
D
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
67.1
76.7
N.A.
73.4
74.2
N.A.
N.A.
64.5
N.A.
64.7
N.A.
28.2
42.2
30
51.6
Protein Similarity:
100
99.1
69.1
87.2
N.A.
84.7
84
N.A.
N.A.
80.5
N.A.
80.1
N.A.
47.2
61
48.1
68.2
P-Site Identity:
100
100
0
66.6
N.A.
86.6
86.6
N.A.
N.A.
66.6
N.A.
13.3
N.A.
33.3
0
6.6
33.3
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
N.A.
46.6
N.A.
46.6
33.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51
47.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
0
0
0
0
8
0
0
8
0
0
8
8
0
% A
% Cys:
8
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
8
36
0
0
15
15
0
0
0
8
8
8
8
8
8
% D
% Glu:
29
15
0
8
0
50
8
8
8
43
0
0
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
8
50
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
15
8
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
8
0
0
50
0
22
8
8
0
8
0
0
% K
% Leu:
0
0
50
0
36
8
0
15
0
15
65
0
8
50
8
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
8
0
8
8
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
36
8
0
8
% N
% Pro:
0
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
8
% Q
% Arg:
15
8
0
8
8
15
15
15
50
8
0
8
0
8
43
% R
% Ser:
0
0
15
29
0
0
8
8
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
22
0
0
0
0
0
0
0
15
0
0
0
% T
% Val:
0
0
0
0
15
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _