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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RER1 All Species: 13.64
Human Site: Y19 Identified Species: 21.43
UniProt: O15258 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15258 NP_008964.3 196 22958 Y19 H G K P S V V Y R F F T R L G
Chimpanzee Pan troglodytes XP_001149559 120 14020
Rhesus Macaque Macaca mulatta XP_001084242 203 23396 Y19 H G K P S V V Y R F F T R L G
Dog Lupus familis XP_851339 142 16730
Cat Felis silvestris
Mouse Mus musculus Q9CQU3 196 22970 Y19 H G K P S V V Y R F F S R L G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516135 196 22988 F19 H G K P S V V F R F F T R L G
Chicken Gallus gallus Q5ZHM5 196 23014 Y19 H G K P S V V Y R F F T R L G
Frog Xenopus laevis NP_001086840 198 23033 F19 H G K P S V V F R F F S R L G
Zebra Danio Brachydanio rerio NP_956969 196 22735 G19 H G K P S A I G N F F K R L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001138110 242 27534 Q19 G G V K K F F Q R L S Q T Y Q
Honey Bee Apis mellifera XP_393582 195 23282 I20 R N V F S Q A I G R I S Q L Y
Nematode Worm Caenorhab. elegans P52879 191 22574 L19 T S R F F H S L E V K Y Q Y Y
Sea Urchin Strong. purpuratus XP_784416 197 23075 R19 S Q P S F F S R V F T S I S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48670 191 21958 E21 P V Q Q R A H E A W R I Y Q H
Baker's Yeast Sacchar. cerevisiae P25560 188 22252 K20 S S N P L I T K M N T M K L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.6 83.7 69.3 N.A. 96.4 N.A. N.A. 95.4 94.3 88.3 84.1 N.A. 51.6 60.2 59.6 60.9
Protein Similarity: 100 58.6 85.7 70.4 N.A. 98.9 N.A. N.A. 98.4 98.4 97.4 92.8 N.A. 61.9 75 73.4 77.1
P-Site Identity: 100 0 100 0 N.A. 93.3 N.A. N.A. 93.3 100 86.6 66.6 N.A. 13.3 13.3 0 6.6
P-Site Similarity: 100 0 100 0 N.A. 100 N.A. N.A. 100 100 100 73.3 N.A. 13.3 26.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 52.5 41.8 N.A.
Protein Similarity: N.A. N.A. N.A. 68.8 65.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 14 7 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 14 14 14 7 14 0 54 47 0 0 0 0 % F
% Gly: 7 54 0 0 0 0 0 7 7 0 0 0 0 0 47 % G
% His: 47 0 0 0 0 7 7 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 7 7 7 0 0 7 7 7 0 0 % I
% Lys: 0 0 47 7 7 0 0 7 0 0 7 7 7 0 0 % K
% Leu: 0 0 0 0 7 0 0 7 0 7 0 0 0 60 7 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 0 7 7 0 0 0 0 0 % N
% Pro: 7 0 7 54 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 7 7 0 7 0 7 0 0 0 7 14 7 14 % Q
% Arg: 7 0 7 0 7 0 0 7 47 7 7 0 47 0 0 % R
% Ser: 14 14 0 7 54 0 14 0 0 0 7 27 0 7 0 % S
% Thr: 7 0 0 0 0 0 7 0 0 0 14 27 7 0 0 % T
% Val: 0 7 14 0 0 40 40 0 7 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 27 0 0 0 7 7 14 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _