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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RER1
All Species:
28.18
Human Site:
Y59
Identified Species:
44.29
UniProt:
O15258
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15258
NP_008964.3
196
22958
Y59
F
V
Y
M
I
R
V
Y
L
L
Q
G
W
Y
I
Chimpanzee
Pan troglodytes
XP_001149559
120
14020
Rhesus Macaque
Macaca mulatta
XP_001084242
203
23396
Y59
F
V
Y
M
I
R
V
Y
L
L
Q
G
W
Y
I
Dog
Lupus familis
XP_851339
142
16730
A16
G
W
Y
I
V
T
Y
A
L
G
I
Y
H
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQU3
196
22970
Y59
F
V
Y
M
I
R
V
Y
L
L
Q
G
W
Y
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516135
196
22988
Y59
F
I
Y
M
I
R
V
Y
L
L
Q
G
W
Y
I
Chicken
Gallus gallus
Q5ZHM5
196
23014
Y59
F
I
Y
M
I
R
V
Y
L
L
Q
G
W
Y
I
Frog
Xenopus laevis
NP_001086840
198
23033
Y59
A
I
Y
M
I
R
V
Y
I
L
Q
G
W
Y
I
Zebra Danio
Brachydanio rerio
NP_956969
196
22735
Y59
A
I
Y
M
I
R
V
Y
I
L
Q
G
W
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138110
242
27534
G59
L
R
I
F
I
Y
Q
G
W
Y
I
V
C
Y
A
Honey Bee
Apis mellifera
XP_393582
195
23282
E60
F
L
R
V
F
L
S
E
G
W
Y
I
V
T
Y
Nematode Worm
Caenorhab. elegans
P52879
191
22574
Y59
I
I
L
L
Q
G
F
Y
I
V
A
Y
A
V
G
Sea Urchin
Strong. purpuratus
XP_784416
197
23075
F59
I
Y
L
L
R
I
F
F
I
Q
G
W
F
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48670
191
21958
F61
R
V
Y
Y
I
Q
G
F
Y
I
I
A
Y
G
L
Baker's Yeast
Sacchar. cerevisiae
P25560
188
22252
A60
F
M
V
R
I
T
M
A
E
G
W
Y
V
I
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.6
83.7
69.3
N.A.
96.4
N.A.
N.A.
95.4
94.3
88.3
84.1
N.A.
51.6
60.2
59.6
60.9
Protein Similarity:
100
58.6
85.7
70.4
N.A.
98.9
N.A.
N.A.
98.4
98.4
97.4
92.8
N.A.
61.9
75
73.4
77.1
P-Site Identity:
100
0
100
13.3
N.A.
100
N.A.
N.A.
93.3
93.3
80
80
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
0
100
26.6
N.A.
100
N.A.
N.A.
100
100
93.3
93.3
N.A.
13.3
20
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.5
41.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.8
65.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
14
0
0
7
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% E
% Phe:
47
0
0
7
7
0
14
14
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
7
7
7
7
14
7
47
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
14
34
7
7
67
7
0
0
27
7
20
7
0
14
54
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
7
14
14
0
7
0
0
40
47
0
0
0
7
7
% L
% Met:
0
7
0
47
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
7
0
0
7
47
0
0
0
0
% Q
% Arg:
7
7
7
7
7
47
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
14
0
0
0
0
0
0
0
7
0
% T
% Val:
0
27
7
7
7
0
47
0
0
7
0
7
14
7
0
% V
% Trp:
0
7
0
0
0
0
0
0
7
7
7
7
47
0
0
% W
% Tyr:
0
7
60
7
0
7
7
54
7
7
7
20
7
54
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _