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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP1
All Species:
4.55
Human Site:
T681
Identified Species:
14.29
UniProt:
O15259
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15259
NP_000263.2
732
83299
T681
W
A
E
E
E
T
E
T
A
R
W
K
V
I
T
Chimpanzee
Pan troglodytes
XP_515684
733
83523
T682
W
A
E
E
E
T
E
T
A
R
W
R
V
I
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532954
694
78936
A643
W
A
E
E
E
T
E
A
A
R
W
K
V
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY53
687
77017
A636
W
A
E
E
E
T
E
A
A
R
W
K
A
I
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419298
726
82217
A673
W
A
E
E
E
S
E
A
S
R
W
R
V
I
A
Frog
Xenopus laevis
NP_001085200
683
78385
V635
T
E
A
A
R
W
K
V
I
A
E
F
L
R
Q
Zebra Danio
Brachydanio rerio
NP_001070638
667
74543
E623
C
W
A
D
E
E
T
E
S
Q
R
A
R
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782288
622
72000
V578
R
D
S
E
R
W
Q
V
I
S
E
F
L
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
78.5
N.A.
72.6
N.A.
N.A.
N.A.
58.8
55.1
43.5
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
98.9
N.A.
85.5
N.A.
83.4
N.A.
N.A.
N.A.
76.2
72.4
63.6
N.A.
N.A.
N.A.
N.A.
55.3
P-Site Identity:
100
93.3
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
66.6
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
86.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
63
25
13
0
0
0
38
50
13
0
13
13
0
38
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
63
75
75
13
63
13
0
0
25
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
25
0
0
0
0
75
13
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
38
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
13
0
0
0
13
13
% Q
% Arg:
13
0
0
0
25
0
0
0
0
63
13
25
13
13
0
% R
% Ser:
0
0
13
0
0
13
0
0
25
13
0
0
0
0
13
% S
% Thr:
13
0
0
0
0
50
13
25
0
0
0
0
0
0
25
% T
% Val:
0
0
0
0
0
0
0
25
0
0
0
0
50
0
0
% V
% Trp:
63
13
0
0
0
25
0
0
0
0
63
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _