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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHOX All Species: 6.67
Human Site: T87 Identified Species: 12.22
UniProt: O15266 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15266 NP_000442.1 292 32236 T87 E K L K E F G T A R V A E G I
Chimpanzee Pan troglodytes XP_528874 69 8346
Rhesus Macaque Macaca mulatta XP_001102324 355 37643 E134 A T L L L P G E A F R F L V S
Dog Lupus familis XP_855626 291 32098 T86 D K L K E F G T G R A A E G V
Cat Felis silvestris
Mouse Mus musculus P70390 331 34887 S110 E R S R E P G S P R L T E V S
Rat Rattus norvegicus O35750 237 26202 M75 T H Y P D A F M R E E L S Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507913 401 45133 A192 E H L R V P F A K A S G R I S
Chicken Gallus gallus Q9PVX0 317 34038 P92 H Q G R F Q E P Y C P G S A S
Frog Xenopus laevis O42567 325 36295 K100 Y G D P Y S A K T S S E C L S
Zebra Danio Brachydanio rerio O42358 292 32739 G76 D S N K H F D G V C R S T V M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097140 420 45518 P162 P K L A P D K P L L P E E C V
Honey Bee Apis mellifera XP_001120111 373 39859 I158 A K S S D L K I A Q A Q V S K
Nematode Worm Caenorhab. elegans P29506 252 28335 A86 N D T G E S A A K R R R T R T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.6 57.1 95.5 N.A. 58.9 59.9 N.A. 53.6 27.7 27 28 N.A. 35.9 39.4 25.3 N.A.
Protein Similarity: 100 23.6 65 97.9 N.A. 68.5 68.1 N.A. 63 45.7 43 46.2 N.A. 48.8 51.4 38 N.A.
P-Site Identity: 100 0 20 73.3 N.A. 33.3 0 N.A. 13.3 0 0 13.3 N.A. 20 13.3 13.3 N.A.
P-Site Similarity: 100 0 20 86.6 N.A. 60 6.6 N.A. 20 13.3 0 33.3 N.A. 26.6 26.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 0 8 16 16 24 8 16 16 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 16 0 0 8 8 0 % C
% Asp: 16 8 8 0 16 8 8 0 0 0 0 0 0 0 0 % D
% Glu: 24 0 0 0 31 0 8 8 0 8 8 16 31 0 0 % E
% Phe: 0 0 0 0 8 24 16 0 0 8 0 8 0 0 0 % F
% Gly: 0 8 8 8 0 0 31 8 8 0 0 16 0 16 0 % G
% His: 8 16 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 8 % I
% Lys: 0 31 0 24 0 0 16 8 16 0 0 0 0 0 8 % K
% Leu: 0 0 39 8 8 8 0 0 8 8 8 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 16 8 24 0 16 8 0 16 0 0 0 0 % P
% Gln: 0 8 0 0 0 8 0 0 0 8 0 8 0 8 0 % Q
% Arg: 0 8 0 24 0 0 0 0 8 31 24 8 8 8 8 % R
% Ser: 0 8 16 8 0 16 0 8 0 8 16 8 16 8 39 % S
% Thr: 8 8 8 0 0 0 0 16 8 0 0 8 16 0 8 % T
% Val: 0 0 0 0 8 0 0 0 8 0 8 0 8 24 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _