KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTLC2
All Species:
34.55
Human Site:
S412
Identified Species:
69.09
UniProt:
O15270
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15270
NP_004854.1
562
62924
S412
A
V
Y
A
T
S
L
S
P
P
V
V
E
Q
I
Chimpanzee
Pan troglodytes
XP_510095
893
98301
S743
A
V
Y
A
T
S
L
S
P
P
V
V
E
Q
I
Rhesus Macaque
Macaca mulatta
XP_001096042
780
85448
S516
A
V
Y
A
T
S
L
S
P
P
V
V
E
Q
I
Dog
Lupus familis
XP_537524
691
75896
S541
A
V
Y
A
T
S
L
S
A
P
V
V
E
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P97363
560
62963
S410
A
V
Y
A
T
S
M
S
P
P
V
M
E
Q
I
Rat
Rattus norvegicus
NP_001032174
560
62943
S410
A
V
Y
A
T
S
M
S
P
P
V
M
E
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514082
550
62189
C402
A
V
Y
A
T
S
M
C
P
P
I
A
E
Q
I
Chicken
Gallus gallus
NP_001006483
560
62717
S410
A
V
Y
A
T
S
L
S
P
P
V
V
E
Q
I
Frog
Xenopus laevis
NP_001085763
555
62268
S405
S
A
Y
A
T
S
M
S
P
P
V
A
Q
Q
I
Zebra Danio
Brachydanio rerio
NP_001018455
534
60425
M395
V
E
Q
I
I
T
S
M
K
C
I
M
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784261
549
60922
S407
A
T
Y
A
S
S
T
S
A
P
V
V
E
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40970
561
63092
P399
V
S
Y
S
E
S
M
P
A
P
V
L
A
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
68.4
78.8
N.A.
96
95.3
N.A.
70.6
87.5
79.1
76.1
N.A.
N.A.
N.A.
N.A.
58.3
Protein Similarity:
100
62.7
70.5
80.7
N.A.
98.5
98.2
N.A.
82.9
92.5
87.7
86.6
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
100
66.6
0
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
100
86.6
26.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
9
0
84
0
0
0
0
25
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
9
0
0
9
0
0
0
0
0
0
0
75
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
17
0
0
0
75
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
42
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
42
9
0
0
0
25
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
67
92
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
9
92
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
92
9
75
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
75
9
9
0
0
0
0
0
0
0
9
% T
% Val:
17
67
0
0
0
0
0
0
0
0
84
50
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _