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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTLC2
All Species:
28.18
Human Site:
T185
Identified Species:
56.36
UniProt:
O15270
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15270
NP_004854.1
562
62924
T185
Y
L
G
F
A
R
N
T
G
S
C
Q
E
A
A
Chimpanzee
Pan troglodytes
XP_510095
893
98301
T516
Y
L
G
F
A
R
N
T
G
S
C
Q
E
A
A
Rhesus Macaque
Macaca mulatta
XP_001096042
780
85448
T289
Y
L
G
F
A
R
N
T
G
S
C
Q
E
A
A
Dog
Lupus familis
XP_537524
691
75896
T314
Y
L
G
F
A
R
N
T
G
A
C
Q
E
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P97363
560
62963
T183
Y
L
G
F
A
R
N
T
G
S
C
Q
E
A
A
Rat
Rattus norvegicus
NP_001032174
560
62943
T183
Y
L
G
F
A
R
N
T
G
S
C
Q
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514082
550
62189
M179
A
E
A
N
S
Q
S
M
K
T
V
R
E
V
L
Chicken
Gallus gallus
NP_001006483
560
62717
D183
Y
L
G
F
A
Q
N
D
G
T
C
Q
Q
A
A
Frog
Xenopus laevis
NP_001085763
555
62268
T178
Y
L
G
F
A
Q
N
T
G
L
C
A
D
A
S
Zebra Danio
Brachydanio rerio
NP_001018455
534
60425
R179
G
V
G
V
A
G
T
R
Q
E
M
G
N
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784261
549
60922
G181
L
G
F
A
E
N
H
G
P
R
S
D
A
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40970
561
63092
T176
A
Q
S
K
G
Q
C
T
D
A
A
L
E
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
68.4
78.8
N.A.
96
95.3
N.A.
70.6
87.5
79.1
76.1
N.A.
N.A.
N.A.
N.A.
58.3
Protein Similarity:
100
62.7
70.5
80.7
N.A.
98.5
98.2
N.A.
82.9
92.5
87.7
86.6
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
73.3
66.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
93.3
86.6
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
9
75
0
0
0
0
17
9
9
9
67
59
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
67
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
9
0
0
9
9
0
9
% D
% Glu:
0
9
0
0
9
0
0
0
0
9
0
0
67
0
0
% E
% Phe:
0
0
9
67
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
75
0
9
9
0
9
67
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
9
67
0
0
0
0
0
0
0
9
0
9
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
67
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
34
0
0
9
0
0
59
9
0
0
% Q
% Arg:
0
0
0
0
0
50
0
9
0
9
0
9
0
0
0
% R
% Ser:
0
0
9
0
9
0
9
0
0
42
9
0
0
9
9
% S
% Thr:
0
0
0
0
0
0
9
67
0
17
0
0
0
0
0
% T
% Val:
0
9
0
9
0
0
0
0
0
0
9
0
0
17
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _