KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTLC2
All Species:
31.52
Human Site:
T555
Identified Species:
63.03
UniProt:
O15270
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15270
NP_004854.1
562
62924
T555
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Chimpanzee
Pan troglodytes
XP_510095
893
98301
T886
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Rhesus Macaque
Macaca mulatta
XP_001096042
780
85448
R695
P
A
R
H
R
R
S
R
S
Q
S
E
R
G
R
Dog
Lupus familis
XP_537524
691
75896
T684
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P97363
560
62963
T553
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Rat
Rattus norvegicus
NP_001032174
560
62943
T553
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514082
550
62189
Chicken
Gallus gallus
NP_001006483
560
62717
T553
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Frog
Xenopus laevis
NP_001085763
555
62268
T548
L
D
R
P
F
D
E
T
T
Y
E
E
T
E
D
Zebra Danio
Brachydanio rerio
NP_001018455
534
60425
T527
L
D
R
P
F
D
E
T
T
Y
E
E
N
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784261
549
60922
P541
Y
S
R
H
P
L
P
P
L
T
D
K
S
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40970
561
63092
C553
I
R
R
T
P
E
D
C
K
D
D
K
Y
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
68.4
78.8
N.A.
96
95.3
N.A.
70.6
87.5
79.1
76.1
N.A.
N.A.
N.A.
N.A.
58.3
Protein Similarity:
100
62.7
70.5
80.7
N.A.
98.5
98.2
N.A.
82.9
92.5
87.7
86.6
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
0
100
100
86.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
0
100
100
93.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
67
9
0
0
9
17
0
0
0
59
% D
% Glu:
0
0
0
0
0
9
67
0
0
0
67
75
0
67
9
% E
% Phe:
0
0
0
0
67
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
17
0
9
0
% K
% Leu:
67
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
0
67
17
0
9
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
92
0
9
9
0
9
0
0
0
0
9
0
9
% R
% Ser:
0
9
0
0
0
0
9
0
9
0
9
0
9
0
0
% S
% Thr:
0
0
0
9
0
0
0
67
67
9
0
0
59
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
67
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _