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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTLC2
All Species:
26.67
Human Site:
Y162
Identified Species:
53.33
UniProt:
O15270
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15270
NP_004854.1
562
62924
Y162
D
Y
N
W
S
F
K
Y
T
G
N
I
I
K
G
Chimpanzee
Pan troglodytes
XP_510095
893
98301
Y493
D
Y
N
W
S
F
K
Y
T
G
N
I
I
K
G
Rhesus Macaque
Macaca mulatta
XP_001096042
780
85448
Y266
D
Y
N
W
S
F
K
Y
T
G
N
I
I
K
G
Dog
Lupus familis
XP_537524
691
75896
Y291
D
Y
N
W
S
F
K
Y
T
G
N
V
I
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P97363
560
62963
Y160
D
Y
N
W
S
F
K
Y
T
G
N
I
I
K
G
Rat
Rattus norvegicus
NP_001032174
560
62943
Y160
D
Y
N
W
S
F
K
Y
T
G
N
I
I
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514082
550
62189
I156
T
F
R
F
T
G
R
I
I
K
D
V
I
N
M
Chicken
Gallus gallus
NP_001006483
560
62717
Y160
D
Y
N
W
T
F
T
Y
T
G
R
V
I
K
G
Frog
Xenopus laevis
NP_001085763
555
62268
F155
D
Y
N
W
T
F
K
F
T
G
R
V
I
K
G
Zebra Danio
Brachydanio rerio
NP_001018455
534
60425
N156
N
Y
L
G
F
A
E
N
T
G
S
C
A
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784261
549
60922
L158
D
N
F
W
S
F
K
L
T
G
T
T
R
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40970
561
63092
A153
E
Y
F
T
Y
S
G
A
V
Y
P
C
M
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.9
68.4
78.8
N.A.
96
95.3
N.A.
70.6
87.5
79.1
76.1
N.A.
N.A.
N.A.
N.A.
58.3
Protein Similarity:
100
62.7
70.5
80.7
N.A.
98.5
98.2
N.A.
82.9
92.5
87.7
86.6
N.A.
N.A.
N.A.
N.A.
73.1
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
73.3
73.3
20
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
46.6
86.6
93.3
40
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% C
% Asp:
75
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
17
9
9
75
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
9
0
0
84
0
0
0
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
0
0
42
75
0
0
% I
% Lys:
0
0
0
0
0
0
67
0
0
9
0
0
0
75
0
% K
% Leu:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% M
% Asn:
9
9
67
0
0
0
0
9
0
0
50
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
0
0
17
0
9
0
0
% R
% Ser:
0
0
0
0
59
9
0
0
0
0
9
0
0
0
0
% S
% Thr:
9
0
0
9
25
0
9
0
84
0
9
9
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
34
0
0
9
% V
% Trp:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
84
0
0
9
0
0
59
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _